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http://www.repositorio.ufop.br/jspui/handle/123456789/9940| Title: | Biodistribution of free and encapsulated 99mTc-fluconazole in an infection model induced by Candida albicans. |
| Authors: | Assis, Danielle Nogueira de Araújo, Raquel Silva Fuscaldi, Leonardo Lima Diniz, Simone Odília Antunes Fernandes Mosqueira, Vanessa Carla Furtado Cardoso, Valbert Nascimento |
| Keywords: | Candida spp Fluconazole Biodistribution Nanocapsules |
| Issue Date: | 2018 |
| Citation: | ASSIS, D. N. de et al. Biodistribution of free and encapsulated 99mTc-fluconazole in an infection model induced by Candida albicans. Biomedicine & Pharmacotherapy, v. 99, p. 438-444, 2018. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0753332217351478>. Acesso em: 05 abr. 2018. |
| Abstract: | Candida spp is an etiologic agent of fungal infections in hospitals and resistance to treatment with antifungals has been extensively reported. Thus, it is very important to develop formulations that increase effectiveness with low toxicity. In this sense, nanocarriers have been investigated, once they modify drug biodistribution profile. Thus, this study aimed to evaluate the biodistribution of free and encapsulated 99mTc-fluconazole into nanocapsules (NCs) in an experimental immunosuppressed murine model of Candida albicans infection. |
| URI: | http://www.repositorio.ufop.br/handle/123456789/9940 |
| metadata.dc.identifier.uri2: | https://www.sciencedirect.com/science/article/pii/S0753332217351478 |
| ISSN: | 07533322 |
| Appears in Collections: | DEFAR - Artigos publicados em periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ARTIGO_BiodistributionFreeEncapsulated.pdf Restricted Access | 565,93 kB | Adobe PDF | View/Open |
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