Biodistribution of free and encapsulated 99mTc-fluconazole in an infection model induced by Candida albicans.

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dc.contributor.authorAssis, Danielle Nogueira de
dc.contributor.authorAraújo, Raquel Silva
dc.contributor.authorFuscaldi, Leonardo Lima
dc.contributor.authorDiniz, Simone Odília Antunes Fernandes
dc.contributor.authorMosqueira, Vanessa Carla Furtado
dc.contributor.authorCardoso, Valbert Nascimento
dc.date.accessioned2018-05-15T14:12:04Z
dc.date.available2018-05-15T14:12:04Z
dc.date.issued2018
dc.description.abstractCandida spp is an etiologic agent of fungal infections in hospitals and resistance to treatment with antifungals has been extensively reported. Thus, it is very important to develop formulations that increase effectiveness with low toxicity. In this sense, nanocarriers have been investigated, once they modify drug biodistribution profile. Thus, this study aimed to evaluate the biodistribution of free and encapsulated 99mTc-fluconazole into nanocapsules (NCs) in an experimental immunosuppressed murine model of Candida albicans infection.pt_BR
dc.identifier.citationASSIS, D. N. de et al. Biodistribution of free and encapsulated 99mTc-fluconazole in an infection model induced by Candida albicans. Biomedicine & Pharmacotherapy, v. 99, p. 438-444, 2018. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0753332217351478>. Acesso em: 05 abr. 2018.pt_BR
dc.identifier.issn 07533322
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/9940
dc.identifier.uri2https://www.sciencedirect.com/science/article/pii/S0753332217351478pt_BR
dc.language.isoen_USpt_BR
dc.rightsabertopt_BR
dc.subjectCandida spppt_BR
dc.subjectFluconazolept_BR
dc.subjectBiodistributionpt_BR
dc.subjectNanocapsulespt_BR
dc.titleBiodistribution of free and encapsulated 99mTc-fluconazole in an infection model induced by Candida albicans.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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