Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/9940
Title: Biodistribution of free and encapsulated 99mTc-fluconazole in an infection model induced by Candida albicans.
Authors: Assis, Danielle Nogueira de
Araújo, Raquel Silva
Fuscaldi, Leonardo Lima
Diniz, Simone Odília Antunes Fernandes
Mosqueira, Vanessa Carla Furtado
Cardoso, Valbert Nascimento
Keywords: Candida spp
Fluconazole
Biodistribution
Nanocapsules
Issue Date: 2018
Citation: ASSIS, D. N. de et al. Biodistribution of free and encapsulated 99mTc-fluconazole in an infection model induced by Candida albicans. Biomedicine & Pharmacotherapy, v. 99, p. 438-444, 2018. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0753332217351478>. Acesso em: 05 abr. 2018.
Abstract: Candida spp is an etiologic agent of fungal infections in hospitals and resistance to treatment with antifungals has been extensively reported. Thus, it is very important to develop formulations that increase effectiveness with low toxicity. In this sense, nanocarriers have been investigated, once they modify drug biodistribution profile. Thus, this study aimed to evaluate the biodistribution of free and encapsulated 99mTc-fluconazole into nanocapsules (NCs) in an experimental immunosuppressed murine model of Candida albicans infection.
URI: http://www.repositorio.ufop.br/handle/123456789/9940
metadata.dc.identifier.uri2: https://www.sciencedirect.com/science/article/pii/S0753332217351478
ISSN:  07533322
Appears in Collections:DEFAR - Artigos publicados em periódicos

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