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Título : Tin(IV) compounds derivatives of reaction between Organotin(IV), SNCL4 and rutin trihydrate : characterization and hypolipidemic effects.
Autor : Mello, Vanessa Joia de
Maia, José Roberto da Silveira
Oliveira, Tânia Toledo de
Ardisson, José Domingos
Nagem, Tanus Jorge
Ardisson, José Domingos
Patricio, Patrícia Santiago de Oliveira
Lima, Geraldo Magela de
Fecha de publicación : 2004
Citación : MELLO, V. J. de et al. Tin(IV) compounds derivatives of reaction between Organotin(IV), SNCL4 and rutin trihydrate: characterization and hypolipidemic effects. Main Group Metal Chemistry, Israel, v. 27, n.6, p. 309-321, 2004. Disponível em: <https://www.degruyter.com/view/j/mgmc.2004.27.6/mgmc.2004.27.6.309/mgmc.2004.27.6.309.xml>. Acesso em: 20 mai. 2017.
Resumen : Equimolar reactions involving SnClPh3, SnCl2Ph2, SnCl3Ph and SnCl4 and rutin trihydrate (Quercetin-3- rutinoside) produced organotin(IV) polymers, which have been characterized by infrared spectroscopy, 'H, n C and "9Sn NMR, Mössbauer spectroscopy, gel permeation chromatography (GPC), differential scanning calorimetry (DSC) and microanalysis. The NMR ('Η, 13C) and "9Sn Mössbauer spectroscopy have revealed dephenylation of the starting organotin(IV) materials. The overall data have revealed a six-coordination for the Sn(IV) centre in solution as well as in solid state. DSC and GPC techniques have confirmed the formation of macromolecules for those adducts with an average molar mass higher than 7.0x10' g/mol. The hypolipidemic effect of total cholesterol reduction in male New Zealand rabbits was comparable to calcic atorvastatin, a commercial drug for treatment of hyperlipidemic patients.
URI : http://www.repositorio.ufop.br/handle/123456789/8007
metadata.dc.identifier.uri2: https://www.degruyter.com/view/j/mgmc.2004.27.6/mgmc.2004.27.6.309/mgmc.2004.27.6.309.xml
metadata.dc.identifier.doi: https://doi.org/10.1515/MGMC.2004.27.6.309
ISSN : 2191-0219
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