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http://www.repositorio.ufop.br/jspui/handle/123456789/3856
Title: | Evaluation of antimicrobial activity and toxic potential of extracts and triterpenes isolated from Maytenus imbricata. |
Authors: | Rodrigues, Vanessa Gregório Duarte, Lucienir Pains Silva, Grácia Divina de Fátima Silva, Fernando César Góes, Jefferson Vieira de Takahashi, Jacqueline Aparecida Pimenta, Lúcia Pinheiro Santos Vieira Filho, Sidney Augusto |
Keywords: | Maytenus imbricata Celastraceae Pentacyclic triterpenes |
Issue Date: | 2012 |
Citation: | RODRIGUES, V. G. et al. Evaluation of antimicrobial activity and toxic potential of extracts and triterpenes isolated from Maytenus imbricata. Química Nova, v. 35, p. 1375-1380, 2012. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000700017>. Acesso em: 20 ago. 2014. |
Abstract: | The phytochemical study of hexane/ethyl ether (1:1) extract of the roots of M. imbricata, Celastraceae, resulted in the isolation and characterization of six known triterpenes: 11α-hydroxylup-20(29)-en-3-one, previously isolated from this species besides, 3β,11α- di-hydroxylup-20(29)-ene, 3,7-dioxofriedelane, 3-oxo-29-hydroxyfriedelane, tingenone and 6-oxo-tingenol. The chemical structures of these triterpenes were established by spectrometric data (IR, 1H and 13C NMR) and through comparison with literature data. The hexane/ethyl ether (1:1), ethyl acetate and methanol extracts, and 11α-hydroxylup-20(29)-en-3-one, tingenone and 6-oxo-tingenol, showed antimicrobial properties on in vitro assays. All extracts and triterpenes, except 3β,11α-di-hydroxylup-20(29)-ene, presented toxicity demonstrated by the larvicidal effect test using Artemia salina. |
URI: | http://www.repositorio.ufop.br/handle/123456789/3856 |
metadata.dc.identifier.doi: | http://dx.doi.org/10.1590/S0100-40422012000700017 |
ISSN: | 1678-7064 |
metadata.dc.rights.license: | A Sociedade Brasileira de Química dá permissão à UFOP para reproduzir no RI/UFOP, uma cópia em formato eletrônico dos artigos completos, sem nenhuma edição e/ou modificação, publicados na revista Química Nova, que tenham como autores seus alunos e/ou professores. Fonte: Email do editor de 17 set. 2013. |
Appears in Collections: | DEFAR - Artigos publicados em periódicos |
Files in This Item:
File | Description | Size | Format | |
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ARTIGO_EvaluationAntimicrobialActivity.pdf | 1,68 MB | Adobe PDF | View/Open |
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