Dietary total antioxidant capacity is inversely related to central adiposity as well as to metabolic and oxidative stress markers in healthy young adults.

Hermsdorff, Helen Hermana MirandaPuchau, BlancaVolp, Ana Carolina PinheiroBarbosa, Kiriaque Barra FerreiraBressan, JosefinaZulet, Maria AngelesMartínez, José Alfredo2015-03-202015-03-202011Hermsdorff, H. H. M. et al. Dietary total antioxidant capacity is inversely related to central adiposity as well as to metabolic and oxidative stress markers in healthy young adults. Nutrition & Metabolism, v. 8, p. 59, 2011. Disponível em: <http://www.nutritionandmetabolism.com/content/8/1/59>. Acesso em: 08 nov. 2014.1743-7075http://www.repositorio.ufop.br/handle/123456789/4685Background: Dietary total antioxidant capacity (TAC) has been assumed as a useful tool to assess the relationship between the cumulative antioxidant food capacity and several chronic disorders. The aim of this cross-sectional study was to investigate the potential relationships of dietary TAC with adiposity, metabolic and oxidative stress markers in healthy young adults. Methods: This study enrolled 266 healthy subjects (105 men/ 161 women; 22 ± 3 years-old; 22.0 ± 2.7 kg/m2). Dietary intake, anthropometry, blood pressure, lifestyle features, and biochemical data were assessed with validated procedures. Results: In linear regression analyses, dietary TAC values were inversely associated with glycemia, total cholesterol: HDL-c ratio, triglycerides and oxidized-LDL concentrations, and positively associated with HDL-c concentrations, independently of gender, age, smoking status, physical activity, vitamin use supplement, waist circumference, energy intake, fatty acid intake. In addition, plasma TAC was negatively correlated with ox-LDL concentrations (r= -0.20, P = 0.003), independently of the assessed confounding variables. Finally, dietary TAC values were inversely related to waist circumference values (r= -0.17, P = 0.005) as well as to lower mild central obesity occurrence (waist circumference ≥ 80/ 94 cm for women/ men, respectively). Conclusion: Dietary TAC values are inversely associated with glucose and lipid biomarkers as well as with central adiposity measurements in healthy young adults, indicating dietary TAC as a useful tool to assess the health benefits of cumulative antioxidant capacity from food intake. In addition, the independent and inverse relationships of ox-LDL concentrations with dietary and plasma TAC respectively suggest a putative role of antioxidant rich-diet in the link between redox state and atherogenesis at early stage.en-USAntioxidantsCentral obesityOxidative stressArteriosclerosisDietary total antioxidant capacity is inversely related to central adiposity as well as to metabolic and oxidative stress markers in healthy young adults.Artigo publicado em periodicoThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: Nutrition & Metabolism <http://www.nutritionandmetabolism.com/content/8/1/59>. Acesso em: 19 jan. 2014.https://doi.org/10.1186/1743-7075-8-59