Dun, S. L.Chianca Júnior, Deoclécio AlvesDun, Nae J.Yang, J.Chang, Jaw-Kang2015-01-202015-01-202000DUN, S. L. et al. Differential expression of cocaine- and amphetamine-regulated transcript-immunoreactivity in the rat spinal preganglionic nuclei. Neuroscience Letters. Supplement, USA, v. 294, n.3, p. 143-146, 2000. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0304394000015755>. Acesso em: 08 nov. 2014.0304-3940http://www.repositorio.ufop.br/handle/123456789/4283The distribution of cocaine- and amphetamine-regulated transcript-like immunoreactivity (CART-LI) was investigated in the rat spinal cords with the use of an antiserum against the CART peptide fragment 55±102. CART-LI ®bers were concentrated in the super®cial layers of the dorsal horn of all segments. In addition to CART-LI ®bers, intensely labeled somata were detected in the intermediolateral cell column (IML) and other sympathetic preganglionic nuclei of the thoracolumbar segments. In the lumbosacral segments, CART-LI ®bers but not somata were seen in the sacral parasympathetic nucleus. Double-labeling the spinal sections with choline acetyltransferase (ChAT)-antisera and CARTantisera revealed that the large majority of ChAT-positive somata in the sympathetic preganglionic nuclei were CARTpositive, whereas ChAT-positive somata in the parasympathetic preganglionic nuclei were CART-negative. Our results show that CART-LI is selectively expressed in a population of sympathetic preganglionic neurons (SPNs), but not in parasympathetic preganglionic neurons (PPNs) of the rat.en-USNeuronsSpinal cordCell columnArtigo publicado em periodicoO periódico Neuroscience Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3521411315026.https://doi.org/10.1016/S0304-3940(00)01575-5