Castro, Myrella LessioNascimento, Andréa Mendes doIkegaki, MasaharuCosta Neto, Cláudio Miguel daAlencar, Severino Matias deRosalen, Pedro Luiz2012-10-092012-10-092009CASTRO, M. L. et al. Identification of a bioactive compound isolated from Brazilian propolis type 6. Bioorganic & Medicinal Chemistry, v. 17, n. 14, p. 5332-5335, jul. 2009. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0968089609004350>. Acesso em: 09 out. 2012.09680896http://www.repositorio.ufop.br/handle/123456789/1582A prenylated benzophenone, hyperibone A, was isolated from the hexane fraction of Brazilianpropolistype6. Its structure was determined by spectral analysis including 2D NMR. This compound exhibited cytotoxic activity against HeLa tumor cells (IC50 = 0.1756 μM), strong antimicrobial activity (MIC range—0.73–6.6 μg/mL; MBC range—2.92–106 μg/mL) against Streptococcus mutans, Streptococcus sobrinus, Streptococcus oralis, Staphylococcus aureus, and Actinomyces naeslundii, and the results of its cytotoxic and antimicrobial activities were considered good.en-USPrenylated benzophenone hyperibone ABiological activityBrazilian propolisArtigo publicado em periodicoO periódico Bioorganic & Medicinal Chemistry concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3310910618604.