Carneiro, ‪Matheus BatistaVaz, Leonardo GomesAfonso, Luís Carlos CroccoHorta, Maria de Fátima MartinsVieira, Leda Quercia2023-05-032023-05-032021CARNEIRO, M. B. et al. Regulation of macrophage subsets and cytokine production in leishmaniasis. Cytokine, v. 147, artigo 155309, 2021. Disponível em: <https://www.sciencedirect.com/science/article/pii/S1043466620303252?via%3Dihub>. Acesso em: 11 out. 2022.1043-4666http://www.repositorio.ufop.br/jspui/handle/123456789/16510Macrophages are host cells for parasites of the genus Leishmania where they multiply inside parasitophorous vacuoles. Paradoxically, macrophages are also the cells responsible for killing or controlling parasite growth, if appropriately activated. In this review, we will cover the patterns of macrophage activation and the mechanisms used by the parasite to circumvent being killed. We will highlight the impacts of the vector bite on macrophage activation. Finally, we will discuss the ontogeny of macrophages that are infected by Leishmania spp.en-USrestritoLeishmaniaWound healing macrophagesSupressive macrophagesInflammatory macrophagesMonocytesArtigo publicado em periodicohttps://www.sciencedirect.com/science/article/pii/S1043466620303252?via%3Dihubhttps://doi.org/10.1016/j.cyto.2020.155309