Rodrigues, Vanessa GregórioDuarte, Lucienir PainsSilva, Roqueline RodriguesSilva, Grácia Divina de FátimaSimões, Maria O. MercadanteTakahashi, Jacqueline AparecidaMatildes, Bibiane Lindsay GuimarãesFonseca, Thaisa Helena SilvaGomes, Maria AparecidaVieira Filho, Sidney Augusto2016-01-072016-01-072015RODRIGUES, V. G. et al. Salacia crassifolia (Celastraceae): chemical constituents and antimicrobial activity. Química Nova, v. 2, p. 237-242, 2015. Disponível em: <http://www.scielo.br/scielo.php?pid=S0100-40422015000200237&script=sci_arttext>. Acesso em: 15 out. 2015.1678-7064http://www.repositorio.ufop.br/handle/123456789/6008The phytochemical study of hexane extract from leaves of Salacia crassifolia resulted in the isolation of 3β-palmitoxy-urs-12-ene, 3-oxofriedelane, 3β-hydroxyfriedelane, 3-oxo-28-hydroxyfriedelane, 3-oxo-29-hydroxyfriedelane, 28,29-dihydroxyfriedelan-3-one, 3,4-seco-friedelan-3-oic acid, 3β-hydroxy-olean-9(11):12-diene and the mixture of α-amirin and β-amirin. β-sitosterol, the polymer gutta-percha, squalene and eicosanoic acid were also isolated. The chemical structures of these constituents were established by IR, 1H and 13C NMR spectral data. Crude extracts and the triterpenes were tested against Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis and no activity was observed under the in vitro assay conditions. The hexane, chloroform, ethyl acetate and ethanol crude extracts, and the constituent 3,4-seco-friedelan-3-oic acid and 28,29-dihydroxyfriedelan-3-one showed in vitro antimicrobial activity against Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Streptococcus sanguinis and Candida albicans.en-USArtigo publicado em periodicoA Sociedade Brasileira de Química dá permissão à UFOP para reproduzir no RI/UFOP, uma cópia em formato eletrônico dos artigos completos, sem nenhuma edição e/ou modificação, publicados na revista Química Nova, que tenham como autores seus alunos e/ou professores. Fonte: Email do editor de 17 set. 2013.http://dx.doi.org/10.5935/0100-4042.20150001