Werneck, Francisco ZacaronCoelho, Emerson FilipinoAlmas, Saulo PetersGarcia, Marília Mendes do NascimentoBonfante, Heloina Lamha MachadoLima, Jorge Roberto Perrout deVigário, Patrícia dos SantosMainenti, Miriam Raquel MeiraTeixeira, Patrícia de Fátima dos SantosVaisman, Mário2019-04-252019-04-252018WERNECK, F. Z. et al. Exercise training improves quality of life in women with subclinical hypothyroidism : a randomized clinical trial. Archives of Endocrinology and Metabolism, São Paulo, v. 2, n. 5, p. 530-536, out. 2018. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972018000500530&lng=en&nrm=iso&tlng=en>. Acesso em: 20 fev. 2019.0004-2730http://www.repositorio.ufop.br/handle/123456789/11134Objective: The aim was to evaluate the quality of life (HRQoL) in women with subclinical hypothyroidism (sHT) after 16 weeks of endurance training. Subjects and methods: In the first phase, a cross-sectional study was conducted in which 22 women with sHT (median age: 41.5 (interquartile range: 17.5) years, body mass index: 26.2 (8.7) kg/m2 , thyroid stimulating hormone > 4.94 mIU/L and free thyroxine between 0.8 and 1.3 ng/dL were compared to a group of 33 euthyroid women concerned to HRQoL. In the second phase, a randomized clinical trial was conducted where only women with sHT were randomly divided into two groups: sHT-Tr (n = 10) – participants that performed an exercise program – and sHT-Sed (n = 10) – controls. Exercise training consisted of 60 minutes of aerobic activities (bike and treadmill), three times a week, for 16 weeks. The HRQoL was assessed by the SF-36 questionnaire in the early and at the end of four months. Results: Women with sHT had lower scores on functional capacity domain in relation to the euthyroid ones (77.0 ± 23.0 vs. 88.8 ± 14.6; p = 0.020). The sHT-Tr group improved functional capacity, general health, emotional aspects, mental and physical component of HRQoL after training period, while the sHT-Sed group showed no significant changes. Conclusion: After 16 weeks of aerobic exercise training, there were remarkable improvements in HRQoL in women with sHT.en-USabertoQuality of lifeFunctional capacityArtigo publicado em periodicoTodo o conteúdo do periódico Arquivos Brasileiros de Endocrinologia e Metabologia, exceto onde identificado, está licenciado sob uma licença Creative Commons 4.0 que permite copiar, distribuir e transmitir o trabalho em qualquer suporte ou formato desde que sejam citados o autor e o licenciante. Fonte: Arquivos Brasileiros de Endocrinologia e Metabologia <http://www.scielo.br/scielo.php?script=sci_serial&pid=0004-2730&lng=en&nrm=iso>. Acesso em: 17 out. 2016.