Silva, Marlene Lourenço daStehmann, João RenatoSerafim, Mateus Sá MagalhãesVale, Valdicley VieiraGontijo, Douglas da CostaBrandão, Geraldo CélioKroon, Erna GeessienOliveira, Alaíde Braga de2020-05-222020-05-222019SILVA, M. L. et al. Himatanthus bracteatus stem extracts present antiflavivirus activity while an isolated sesquiterpene glucoside present only anti-Zika virus activity in vitro. Natural Product Research, nov. 2019. Disponível em: <https://www.tandfonline.com/doi/full/10.1080/14786419.2019.1690487>. Acesso em: 10 fev. 2020.1478-6427http://www.repositorio.ufop.br/handle/123456789/12239The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective indexes (SI) > 10 and its fractionation led to the isolation of the known plumieride that was active only against Zika virus (SI of 15.97).en-USrestritoYellow fever virusPlumierideSpectroscopic analysesArtigo publicado em periodicohttps://www.tandfonline.com/doi/full/10.1080/14786419.2019.1690487https://doi.org/10.1080/14786419.2019.1690487