The role of key genes and pathways involved in the tumorigenesis of Malignant Mesothelioma.

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dc.contributor.authorAssis, Leonardo Vinícius Monteiro de
dc.contributor.authorLocatelli, Jamille
dc.contributor.authorIsoldi, Mauro César
dc.date.accessioned2015-04-01T17:33:20Z
dc.date.available2015-04-01T17:33:20Z
dc.date.issued2014
dc.description.abstractMalignant Mesothelioma (MM) is a very aggressive cancer with low survival rates and often diagnosed at an advanced stage. Several players have been implicated in the development of this cancer, such as asbestos, erionite and the simian virus 40 (SV40). Here, we have reviewed the involvement of erionite, SV40, aswell as, the role of several genes (p16INK4a, p14ARF, NF2, LATS2, SAV, CTNNB1 and among others), the pathways (RAS, PI3K,Wnt, BCL and Hippo), and their respective roles in the development of MM.pt_BR
dc.identifier.citationASSIS, L. V. M. de; LOCATELLI, J.; ISOLDI, M. C. The role of key genes and pathways involved in the tumorigenesis of Malignant Mesothelioma. Biochimica et Biophysica Acta, v. 1845, p. 232-247, 2014. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0304419X14000158>. Acesso em: 08 nov. 2014.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.bbcan.2014.01.008
dc.identifier.issn0304-419X
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/4925
dc.language.isoen_USpt_BR
dc.rights.licenseO periódico Biochimica et Biophysica Acta concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3546550210429.pt_BR
dc.subjectMalignant Mesotheliomapt_BR
dc.subjectErionite/SV40pt_BR
dc.subjectGenes and pathwayspt_BR
dc.titleThe role of key genes and pathways involved in the tumorigenesis of Malignant Mesothelioma.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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