Identification of a bioactive compound isolated from Brazilian propolis type 6.

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dc.contributor.authorCastro, Myrella Lessio
dc.contributor.authorNascimento, Andréa Mendes do
dc.contributor.authorIkegaki, Masaharu
dc.contributor.authorCosta Neto, Cláudio Miguel da
dc.contributor.authorAlencar, Severino Matias de
dc.contributor.authorRosalen, Pedro Luiz
dc.date.accessioned2012-10-09T12:29:02Z
dc.date.available2012-10-09T12:29:02Z
dc.date.issued2009
dc.description.abstractA prenylated benzophenone, hyperibone A, was isolated from the hexane fraction of Brazilianpropolistype6. Its structure was determined by spectral analysis including 2D NMR. This compound exhibited cytotoxic activity against HeLa tumor cells (IC50 = 0.1756 μM), strong antimicrobial activity (MIC range—0.73–6.6 μg/mL; MBC range—2.92–106 μg/mL) against Streptococcus mutans, Streptococcus sobrinus, Streptococcus oralis, Staphylococcus aureus, and Actinomyces naeslundii, and the results of its cytotoxic and antimicrobial activities were considered good.pt_BR
dc.identifier.citationCASTRO, M. L. et al. Identification of a bioactive compound isolated from Brazilian propolis type 6. Bioorganic & Medicinal Chemistry, v. 17, n. 14, p. 5332-5335, jul. 2009. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0968089609004350>. Acesso em: 09 out. 2012.pt_BR
dc.identifier.issn09680896
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/1582
dc.language.isoen_USpt_BR
dc.rights.licenseO periódico Bioorganic & Medicinal Chemistry concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3310910618604.
dc.subjectPrenylated benzophenone hyperibone Apt_BR
dc.subjectBiological activitypt_BR
dc.subjectBrazilian propolispt_BR
dc.titleIdentification of a bioactive compound isolated from Brazilian propolis type 6.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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