Identification of a bioactive compound isolated from Brazilian propolis type 6.
dc.contributor.author | Castro, Myrella Lessio | |
dc.contributor.author | Nascimento, Andréa Mendes do | |
dc.contributor.author | Ikegaki, Masaharu | |
dc.contributor.author | Costa Neto, Cláudio Miguel da | |
dc.contributor.author | Alencar, Severino Matias de | |
dc.contributor.author | Rosalen, Pedro Luiz | |
dc.date.accessioned | 2012-10-09T12:29:02Z | |
dc.date.available | 2012-10-09T12:29:02Z | |
dc.date.issued | 2009 | |
dc.description.abstract | A prenylated benzophenone, hyperibone A, was isolated from the hexane fraction of Brazilianpropolistype6. Its structure was determined by spectral analysis including 2D NMR. This compound exhibited cytotoxic activity against HeLa tumor cells (IC50 = 0.1756 μM), strong antimicrobial activity (MIC range—0.73–6.6 μg/mL; MBC range—2.92–106 μg/mL) against Streptococcus mutans, Streptococcus sobrinus, Streptococcus oralis, Staphylococcus aureus, and Actinomyces naeslundii, and the results of its cytotoxic and antimicrobial activities were considered good. | pt_BR |
dc.identifier.citation | CASTRO, M. L. et al. Identification of a bioactive compound isolated from Brazilian propolis type 6. Bioorganic & Medicinal Chemistry, v. 17, n. 14, p. 5332-5335, jul. 2009. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0968089609004350>. Acesso em: 09 out. 2012. | pt_BR |
dc.identifier.issn | 09680896 | |
dc.identifier.uri | http://www.repositorio.ufop.br/handle/123456789/1582 | |
dc.language.iso | en_US | pt_BR |
dc.rights.license | O periódico Bioorganic & Medicinal Chemistry concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3310910618604. | |
dc.subject | Prenylated benzophenone hyperibone A | pt_BR |
dc.subject | Biological activity | pt_BR |
dc.subject | Brazilian propolis | pt_BR |
dc.title | Identification of a bioactive compound isolated from Brazilian propolis type 6. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
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