A tetravalent dengue nanoparticle stimulates antibody production in mice.
dc.contributor.author | Silva, Elisângela F. | |
dc.contributor.author | Orsi, Mariana | |
dc.contributor.author | Andrade, Ângela Leão | |
dc.contributor.author | Domingues, Rosana Zacarias | |
dc.contributor.author | Silva, Breno de Mello | |
dc.contributor.author | Araújo, Helena Rocha Corrêa de | |
dc.contributor.author | Pimenta, Paulo Filemon Paolucci | |
dc.contributor.author | Diamond, Michael S. | |
dc.contributor.author | Rocha, Eliseu S. O. | |
dc.contributor.author | Kroon, Erna Geessien | |
dc.contributor.author | Malaquias, Luiz Cosme Cotta | |
dc.contributor.author | Coelho, Luiz Felipe Leomil | |
dc.date.accessioned | 2017-03-16T13:34:41Z | |
dc.date.available | 2017-03-16T13:34:41Z | |
dc.date.issued | 2012 | |
dc.description.abstract | Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However, a subset of patients experiencing secondary infection with a different serotype progresses to the severe form of the disease, dengue hemorrhagic fever/dengue shock syndrome. Currently, there are no licensed vaccines or antiviral drugs to prevent or treat dengue infections. Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines. | pt_BR |
dc.identifier.citation | SILVA, E. F. et al. A tetravalent dengue nanoparticle stimulates antibody production in mice. Journal of Nanobiotechnology, v. 10, p. 13, 2012. Disponível em: <https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-10-13> Acesso em: 19 fev. 2017. | pt_BR |
dc.identifier.doi | https://doi.org/10.1186/1477-3155-10-13 | |
dc.identifier.issn | 1477-3155 | |
dc.identifier.uri | http://www.repositorio.ufop.br/handle/123456789/7383 | |
dc.language.iso | pt_BR | pt_BR |
dc.rights | aberto | pt_BR |
dc.rights.license | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: o próprio artigo. | pt_BR |
dc.subject | Inactivated Dengue vírus | pt_BR |
dc.subject | Nanoparticles | pt_BR |
dc.subject | Humoral response | pt_BR |
dc.title | A tetravalent dengue nanoparticle stimulates antibody production in mice. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
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