A tetravalent dengue nanoparticle stimulates antibody production in mice.

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dc.contributor.authorSilva, Elisângela F.
dc.contributor.authorOrsi, Mariana
dc.contributor.authorAndrade, Ângela Leão
dc.contributor.authorDomingues, Rosana Zacarias
dc.contributor.authorSilva, Breno de Mello
dc.contributor.authorAraújo, Helena Rocha Corrêa de
dc.contributor.authorPimenta, Paulo Filemon Paolucci
dc.contributor.authorDiamond, Michael S.
dc.contributor.authorRocha, Eliseu S. O.
dc.contributor.authorKroon, Erna Geessien
dc.contributor.authorMalaquias, Luiz Cosme Cotta
dc.contributor.authorCoelho, Luiz Felipe Leomil
dc.date.accessioned2017-03-16T13:34:41Z
dc.date.available2017-03-16T13:34:41Z
dc.date.issued2012
dc.description.abstractDengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However, a subset of patients experiencing secondary infection with a different serotype progresses to the severe form of the disease, dengue hemorrhagic fever/dengue shock syndrome. Currently, there are no licensed vaccines or antiviral drugs to prevent or treat dengue infections. Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines.pt_BR
dc.identifier.citationSILVA, E. F. et al. A tetravalent dengue nanoparticle stimulates antibody production in mice. Journal of Nanobiotechnology, v. 10, p. 13, 2012. Disponível em: <https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-10-13> Acesso em: 19 fev. 2017.pt_BR
dc.identifier.doihttps://doi.org/10.1186/1477-3155-10-13
dc.identifier.issn1477-3155
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/7383
dc.language.isopt_BRpt_BR
dc.rightsabertopt_BR
dc.rights.licenseThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: o próprio artigo.pt_BR
dc.subjectInactivated Dengue víruspt_BR
dc.subjectNanoparticlespt_BR
dc.subjectHumoral responsept_BR
dc.titleA tetravalent dengue nanoparticle stimulates antibody production in mice.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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