Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
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Data
2004
Autores
Santiago, Helton da Costa
Oliveira, Carolina Ferreira
Santiago, Luciana
Ferraz, Fernanda Oliveira
Souza, Daniele da Glória de
Freitas, Luiz Antônio Rodrigues de
Afonso, Luís Carlos Crocco
Teixeira, Mauro Martins
Gazzinelli, Ricardo Tostes
Vieira, Leda Quercia
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Resumo
The expression and putative role of chemokines during infection with Leishmania major in mice were
investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible
to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.
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SANTIAGO, H. da C. Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major. Infection and Immunity, v. 72, n.8, p. 4918-4923, 2004. Disponível em: <http://iai.asm.org/content/72/8/4918>. Acesso em: 19 fev. 2017.