Silymarin : not just another antioxidant.
dc.contributor.author | Camini, Fernanda Caetano | |
dc.contributor.author | Costa, Daniela Caldeira | |
dc.date.accessioned | 2021-10-18T17:36:40Z | |
dc.date.available | 2021-10-18T17:36:40Z | |
dc.date.issued | 2020 | pt_BR |
dc.description.abstract | Silymarin (Silybum marianum; SM), popularly known as milk thistle, is an extract that has been used for many centuries to treat liver diseases. In recent years, several studies have shown that SM is not only just another antioxidant but also a multifunctional compound that exhibits several beneficial properties for use in the treatment and prevention of different types of pathologies and disorders. This review aims at demonstrating the main protective activities of SM in diseases, such as cancer, diabetes, hepatitis, non-alcoholic fatty liver disease, alcoholic liver disease, hepatitis C virus, hepatitis B virus, metabolic syndrome, depression, cardiovascular diseases and thalassemia, in addition to its photoprotective activity in in vitro tests and preclinical studies. Its main functions include antioxidant and anti-inflammatory effects, and it acts as modulator of signaling pathways. It has been suggested that SM presents great multifunctional potential and is capable of achieving promising results in different types of research. However, caution is still needed regarding its indiscriminate use in humans as there are only a few clinical studies relating to the adequate dose and the actual efficacy of this extract in different types of diseases. | pt_BR |
dc.identifier.citation | CAMINI, F. C.; COSTA, D. C. Silymarin: not just another antioxidant. Journal of Basic and Clinical Physiology and Pharmacology, artigo 20190206, 2020. Disponível em: <https://www.degruyter.com/document/doi/10.1515/jbcpp-2019-0206/html>. Acesso em: 10 jun. 2021. | pt_BR |
dc.identifier.doi | https://doi.org/10.1515/jbcpp-2019-0206 | pt_BR |
dc.identifier.issn | 2191-0286 | |
dc.identifier.uri | http://www.repositorio.ufop.br/jspui/handle/123456789/13880 | |
dc.identifier.uri2 | https://www.degruyter.com/document/doi/10.1515/jbcpp-2019-0206/html | pt_BR |
dc.language.iso | en_US | pt_BR |
dc.rights | restrito | pt_BR |
dc.subject | Anti-inflammatory | pt_BR |
dc.subject | Milk thistle | pt_BR |
dc.subject | Silybum marianum | pt_BR |
dc.title | Silymarin : not just another antioxidant. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
Arquivos
Pacote Original
1 - 1 de 1
Nenhuma Miniatura disponível
- Nome:
- ARTIGO_SilymarinAnotherAntioxidant.pdf
- Tamanho:
- 3.42 MB
- Formato:
- Adobe Portable Document Format
- Descrição:
Licença do Pacote
1 - 1 de 1
Nenhuma Miniatura disponível
- Nome:
- license.txt
- Tamanho:
- 1.71 KB
- Formato:
- Item-specific license agreed upon to submission
- Descrição: