Evaluation of antimicrobial activity and toxic potential of extracts and triterpenes isolated from Maytenus imbricata.
dc.contributor.author | Rodrigues, Vanessa Gregório | |
dc.contributor.author | Duarte, Lucienir Pains | |
dc.contributor.author | Silva, Grácia Divina de Fátima | |
dc.contributor.author | Silva, Fernando César | |
dc.contributor.author | Góes, Jefferson Vieira de | |
dc.contributor.author | Takahashi, Jacqueline Aparecida | |
dc.contributor.author | Pimenta, Lúcia Pinheiro Santos | |
dc.contributor.author | Vieira Filho, Sidney Augusto | |
dc.date.accessioned | 2014-11-14T18:21:58Z | |
dc.date.available | 2014-11-14T18:21:58Z | |
dc.date.issued | 2012 | |
dc.description.abstract | The phytochemical study of hexane/ethyl ether (1:1) extract of the roots of M. imbricata, Celastraceae, resulted in the isolation and characterization of six known triterpenes: 11α-hydroxylup-20(29)-en-3-one, previously isolated from this species besides, 3β,11α- di-hydroxylup-20(29)-ene, 3,7-dioxofriedelane, 3-oxo-29-hydroxyfriedelane, tingenone and 6-oxo-tingenol. The chemical structures of these triterpenes were established by spectrometric data (IR, 1H and 13C NMR) and through comparison with literature data. The hexane/ethyl ether (1:1), ethyl acetate and methanol extracts, and 11α-hydroxylup-20(29)-en-3-one, tingenone and 6-oxo-tingenol, showed antimicrobial properties on in vitro assays. All extracts and triterpenes, except 3β,11α-di-hydroxylup-20(29)-ene, presented toxicity demonstrated by the larvicidal effect test using Artemia salina. | pt_BR |
dc.identifier.citation | RODRIGUES, V. G. et al. Evaluation of antimicrobial activity and toxic potential of extracts and triterpenes isolated from Maytenus imbricata. Química Nova, v. 35, p. 1375-1380, 2012. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000700017>. Acesso em: 20 ago. 2014. | pt_BR |
dc.identifier.doi | http://dx.doi.org/10.1590/S0100-40422012000700017 | |
dc.identifier.issn | 1678-7064 | |
dc.identifier.uri | http://www.repositorio.ufop.br/handle/123456789/3856 | |
dc.language.iso | en_US | pt_BR |
dc.rights.license | A Sociedade Brasileira de Química dá permissão à UFOP para reproduzir no RI/UFOP, uma cópia em formato eletrônico dos artigos completos, sem nenhuma edição e/ou modificação, publicados na revista Química Nova, que tenham como autores seus alunos e/ou professores. Fonte: Email do editor de 17 set. 2013. | pt_BR |
dc.subject | Maytenus imbricata | pt_BR |
dc.subject | Celastraceae | pt_BR |
dc.subject | Pentacyclic triterpenes | pt_BR |
dc.title | Evaluation of antimicrobial activity and toxic potential of extracts and triterpenes isolated from Maytenus imbricata. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
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