Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/9928
Title: Antibacterial activity of extract and fractions from branches of Protium spruceanum and cytotoxicity on fibroblasts.
Authors: Amparo, Tatiane Roquete
Rodrigues, Ivanildes Vasconcelos
Seibert, Janaína Brandão
Souza, Rafaella Hilda Zaniti
Oliveira, Amanda Ribeiro de
Cabral, Vivette Appolinário Rodrigues
Vieira, Paula Melo de Abreu
Brandão, Geraldo Célio
Okuma, Adriana Akemi
Vieira Filho, Sidney Augusto
Teixeira, Luiz Fernando de Medeiros
Souza, Gustavo Henrique Bianco de
Keywords: Protium spruceanum
Cytotoxicity
Antbacterial activity
Issue Date: 2017
Citation: AMPARO, T. R. et al. Antibacterial activity of extract and fractions from branches of Protium spruceanum and cytotoxicity on fibroblasts. Natural Product Research, v. 01, p. 1-5, 2017. Disponível em: <https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1354182?journalCode=gnpl20>. Acesso em: 05 abr. 2018.
Abstract: The crude ethanol extract (CEE) and fractions from branches of Protium spruceanum were subjected to antibacterial and cytotoxicity assays. Compounds of the most active fraction were identified by GC-MS and LC-MS. CEE was active against 19 bacteria and the ethyl acetate fraction (EAF) showed the lowest minimum bactericidal concentration (MBC 0.3–80.0 mg/mL). Through time-kill assay was observed that EAF induced rapid bactericidal effect against Staphylococcus saprophyticus. The cytotoxicity tests against L929 fibroblasts showed great potential of EAF on the treatment of infections caused by five bacteria (MBC < IC50). The results provide in vitro scientific support to the possible application of branches of P. spruceanum as antimicrobial agent that may contribute for treatment of infections.
URI: http://www.repositorio.ufop.br/handle/123456789/9928
metadata.dc.identifier.uri2: https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1354182?journalCode=gnpl20
ISSN: 14786427
Appears in Collections:DEFAR - Artigos publicados em periódicos

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