Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/972
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dc.contributor.authorGiunchetti, Rodolfo Cordeiro-
dc.contributor.authorMayrink, Wilson-
dc.contributor.authorCarneiro, Cláudia Martins-
dc.contributor.authorOliveira, Rodrigo Corrêa de-
dc.contributor.authorMartins Filho, Olindo Assis-
dc.contributor.authorMarques, Marcos José-
dc.contributor.authorTafuri, Wagner Luiz-
dc.contributor.authorReis, Alexandre Barbosa-
dc.date.accessioned2012-07-05T12:16:59Z-
dc.date.available2012-07-05T12:16:59Z-
dc.date.issued2008-
dc.identifier.citationGIUNCHETTI, R. C. et al. Histopathological and immunohistochemical investigations of the hepatic compartment associated with parasitism and serum biochemical changes in canine visceral leishmaniasis. Veterinary Science, v. 84, n. 2, p. 269-277, abr. 2008. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0034528807001245>. Acesso em: 05 jul. 2012.pt_BR
dc.identifier.issn03784312-
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/972-
dc.description.abstractThe immunopathological evaluation of the hepatic compartment associated with parasitism and biochemical findings are essential for understanding the genesis of hepatomegaly in anine visceral leishmaniasis (CVL). Three clinical groups of dogs naturally infected with Leishmania chagasi[i.e., asymptomatic (AD, n = 12), oligosymptomatic (OD,n = 12) and symptomatic (SD,n = 17)] were assessed and compared with a group of non-infected dogs (NID,n = 11). Intense reaction of the Kupffer cells, capsule and portal inflammation, and the presence of intralobular granulomas, were observed in the different clinical groups. Dogs in the SD group presented a higher frequency of parasitism compared with the AD group. Inflammatory alterations were more intense in the SD group and were associated with parasit-ism. Our results indicated an association between histological liver changes and the progression of biochemical alterations according to pro-gression of clinical forms of CVL, and the direct relationship between clinical symptoms and frequency of hepatic parasitism.pt_BR
dc.language.isoen_USpt_BR
dc.subjectDogpt_BR
dc.subjectHistopathologypt_BR
dc.subjectImmunohistochemistrypt_BR
dc.subjectLeishmania chagasipt_BR
dc.subjectLiverpt_BR
dc.titleHistopathological and immunohistochemical investigations of the hepatic compartment associated with parasitism and serum biochemical changes in canine visceral leishmaniasis.pt_BR
dc.typeArtigo publicado em periodicopt_BR
dc.rights.licenseO periódico Research in Veterinary Science concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3281420662301.-
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