Please use this identifier to cite or link to this item:
http://www.repositorio.ufop.br/jspui/handle/123456789/9609| Title: | Synthesis of an uncharged tetra-cyclopeptide acting as a transmembrane carrier : enhanced cellular and nuclear uptake. |
| Authors: | Hilário, Flaviane Francisco Traoré, Mohamed Dit Mady Zwick, Vincent Berry, Laurence Pires, Claudia A. Simões Cuendet, Muriel Fantozzi, Nicolas Freitas, Rossimiriam Pereira de Maynadier, Marjorie Wein, Sharon Vial, Henri Wong, Yung-Sing |
| Issue Date: | 2017 |
| Citation: | HILÁRIO, F. F. et al. Synthesis of an uncharged tetra-cyclopeptide acting as a transmembrane carrier: enhanced cellular and nuclear uptake. Organic Letters, v. 19, p. 1-4, 2017. Disponível em: <http://pubs.acs.org/doi/ipdf/10.1021/acs.orglett.6b03776>. Acesso em: 15 set. 2017. |
| Abstract: | A small uncharged cyclopeptide scaffold inspired by a natural product and designed to undergo postfunctionalizations was used as a new transmembrane vector. A bioactive and fluorescent triazole aminocoumarin was bound to this carrier to facilitate its moving across cell and subcellular membranes, and this led to an increase in its cell toxicity. |
| URI: | http://www.repositorio.ufop.br/handle/123456789/9609 |
| metadata.dc.identifier.uri2: | http://pubs.acs.org/doi/ipdf/10.1021/acs.orglett.6b03776 |
| metadata.dc.identifier.doi: | https://doi.org/10.1021/acs.orglett.6b03776 |
| ISSN: | 1523-7052 |
| Appears in Collections: | DEQUI - Artigos publicados em periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ARTIGO_SynthesisUnchargedTetra.pdf Restricted Access | 1,42 MB | Adobe PDF | View/Open |
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