Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/9152
Title: Comparison between two markers in the identification of free plasma DNA fractions in pacients with breast cancer.
Authors: Sediyama, Catarina Maria Nogueira de Oliveira
Abranches, Monise Viana
Moraes, Luís Fernando de Sousa
Freitas, Renata Nascimento de
Ribeiro, Andréia Queiroz
Paula, Sérgio Oliveira de
Peluzio, Maria do Carmo Gouveia
Issue Date: 2016
Citation: SEDIYAMA, C. M. N. O et al. Comparison between two markers in the identification of free plasma DNA fractions in pacients with breast cancer. International Journal of New Technology and Research, v. 2, p. 82-86, 2016. Disponível em: <https://www.ijntr.org/download_data/IJNTR02050052.pdf>. Acesso em: 29 ago. 2017.
Abstract: Cancer is one of the most cause of death in the world, with increased incidence each year. About 1.7 million women died In 2012, 1.7 million women died in the world with breast cancer. This study aimed to quantify the FDNAF by two markers, the gene expression of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and ß-actin, and evaluate which is the best to detect women with breast cancer.50 women were recruited to dose the FDNAF, 30 with breast cancer and 20 healthy controls. DNA was extracted from plasma, and Real time PCR reaction using the GAPDH and β-actin were performed. The GAPDH was the most adequate marker to identify the patients with breast cancer, because they presented higher levels of fragments of free DNA, when compared to healthy controls.
URI: http://www.repositorio.ufop.br/handle/123456789/9152
metadata.dc.identifier.uri2: https://www.ijntr.org/download_data/IJNTR02050052.pdf
ISSN: 24544116
Appears in Collections:DENCS - Artigos publicados em periódicos

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