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Title: Association between maternal education and blood pressure : mediation evidence through height components in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Authors: Rodríguez López, Santiago
Benseñor, Isabela Judith Martins
Giatti, Luana
Carmen Molina, Maria del
Lotufo, Paulo Andrade
Keywords: Maternal education
Height components
Mediation modelling
Transitioning populations
Issue Date: 2017
Citation: RODRÍGUEZ LÓPEZ, S. et al. Association between maternal education and blood pressure: mediation evidence through height components in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Annals of Human Biology, v. 44, n. 3, p. 1-9, 2017. Disponível em: <>. Acesso em: 29 ago. 2017.
Abstract: Background: Maternal education influences skeletal growth and offspring adult blood pressure (BP). Height components are negatively associated with BP in high-income countries. Aim: To evaluate the association between maternal education and offspring adult systolic and diastolic BP (SBP/DBP), assessing whether different height components might mediate such an association. Subjects and methods: Simple mediation modelling was used to evaluate the maternal education-offspring SBP/DBP association, estimating the contribution of offspring height components, in a cross-sectional sample of 13 571 Brazilians aged 34-75 from the ELSA-Brasil study. Results: After full adjustment for confounders, and compared to participants whose mothers received low education, those whose mothers received high education, had on average, 0.2 mm Hg lower SBP (95% CI: -0.274, -0.132), as result of the link between maternal education and offspring adult height which, in turn, influenced SBP. Thus, 18-26% of the maternal education-SBP association occurred indirectly, through height, trunk and leg length, alternatively. Conclusions: Better maternal education might influence higher leg and trunk lengths in offspring, which in turn, might contribute to prevent higher BP in adults. The negative height-BP association reported in high-income countries is also present in a middle-income country with more recent economic development.
ISSN: 1464-5033
Appears in Collections:DENCS - Artigos publicados em periódicos

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