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Campo Dublin Core | Valor | Idioma |
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dc.contributor.author | Sousa, Grasiely Faria de | - |
dc.contributor.author | Aguiar, Mariana Guerra de | - |
dc.contributor.author | Takahashi, Jacqueline Aparecida | - |
dc.contributor.author | Alves, Tânia Maria de Almeida | - |
dc.contributor.author | Kohlhoff, Markus | - |
dc.contributor.author | Vieira Filho, Sidney Augusto | - |
dc.contributor.author | Silva, Grácia Divina de Fátima | - |
dc.contributor.author | Duarte, Lucienir Pains | - |
dc.date.accessioned | 2017-08-30T18:26:32Z | - |
dc.date.available | 2017-08-30T18:26:32Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | SOUSA, G. F. et al. Flavonol triglycosides of leaves from Maytenus robusta with acetylcholinesterase inhibition. Phytochemistry Letters, v. 19, p. 34-38, 2017. Disponível em: <http://www.sciencedirect.com/science/article/pii/S1874390016302282>. Acesso em: 29 ago. 2017. | pt_BR |
dc.identifier.issn | 1874-3900 | - |
dc.identifier.uri | http://www.repositorio.ufop.br/handle/123456789/8611 | - |
dc.description.abstract | Although Maytenus robusta aqueous infusions of leaves are used in Brazilian traditional medicine for stomach disease treatment, only a few chemical studies of this species are found in literature. The phytochemical investigation of methanol extract from M. robusta leaves yielded the known compound kaempferol (3) and two new flavonol glycosides: kaempferol-3-O-b-D-glucopyranosyl-(1 !3)-a-Lrhamnopyranosyl-( 1 ! 2)-b-D-glucopyranoside (1) and quercetin-3-O-b-D-glucopyranosyl-(1 !3)-a-Lrhamnopyranosyl-( 1 ! 2)-b-D-glucopyranoside (2). The chemical structures of 1 and 2 were elucidated by 1D/2D NMR, ESI–MS and ESI–MS2 spectral data. It is the first time flavonoids have been reported from M. robusta. Flavonols 1 and 2 showed 66% and 80% acetylcholinesterase (AChE) inhibition, compared to 93% of the standard eserine, by the Ellman’s method. These substances are one of the few active flavonols linked to a trisaccharide chain in the literature presenting this activity, and contribute to the screening for new types of natural AChE inhibitors. | pt_BR |
dc.language.iso | en_US | pt_BR |
dc.rights | aberto | pt_BR |
dc.subject | Celastraceae | pt_BR |
dc.title | Flavonol triglycosides of leaves from Maytenus robusta with acetylcholinesterase inhibition. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
dc.rights.license | O periódico Phytochemistry Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 4178720474114. | - |
dc.identifier.doi | https://doi.org/10.1016/j.phytol.2016.10.024 | - |
Aparece nas coleções: | DEFAR - Artigos publicados em periódicos |
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ARTIGO_FlavonolTriglycosidesLeaves.pdf | 344,21 kB | Adobe PDF | Visualizar/Abrir |
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