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Título: | Fortified interpenetrating polymers - bacteria resistant coatings for medical devices. |
Autor(es): | Venkateswaran, Seshasailam Santos, Orlando David Henrique dos Scholefield, Emma Lilienkampf, Annamaria Gwynne, Peter J. Swann, David G. Dhaliwal, Kevin Gallagher, Maurice P. Bradley, Mark |
Data do documento: | 2016 |
Referência: | VENKATESWARAN, S. et al. Fortified interpenetrating polymers - bacteria resistant coatings for medical devices. J Mater Chem B, v. 14, p. 5405-5411, 2016. Disponível em: <http://pubs.rsc.org/en/Content/ArticleLanding/2016/TB/C6TB01110A#!divAbstract>. Acesso em: 29 ago. 2017. |
Resumo: | Infections arising from contaminated medical devices are a serious global issue, contributing to antibiotic resistance and imposing significant strain on healthcare systems. Since the majority of medical deviceassociated infections are biofilm related, efforts are being made to generate either bacteria-repellent or antibacterial coatings aimed at preventing bacterial colonisation. Here, we utilise a nanocapsule mediated slow release of a natural antimicrobial to improve the performance of a bacteria repellent polymer coating. Poly(lauryl acrylate) nanocapsules containing eugenol (4-allyl-2-methoxyphenol) were prepared and entrapped within a interpenetrating network designed to repel bacteria. When coated on a catheter and an endotracheal tube, this hemocompatible system allowed slow-release of eugenol, resulting in notable reduction in surface-bound Klebsiella pneumoniae and methicillin resistant Staphylococcus aureus. |
URI: | http://www.repositorio.ufop.br/handle/123456789/8609 |
DOI: | https://doi.org/10.1039/C6TB01110A |
ISSN: | 2050-7518 |
Licença: | This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Fonte: o próprio artigo. |
Aparece nas coleções: | DEFAR - Artigos publicados em periódicos |
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ARTIGO_FortifiedInterpenetratingPolymer.pdf | 3,37 MB | Adobe PDF | Visualizar/Abrir |
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