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Title: Risk factors for mucosal manifestation of American cutaneous leishmaniasis.
Authors: Coelho, George Luiz Lins Machado
Caiaffa, Waleska Teixeira
Genaro, Odair
Magalhães, Paulo Araújo
Mayrink, Wilson
Keywords: Leishmaniasis
Risk factors
Mucosal lesions
Issue Date: 2003
Citation: COELHO, G. L. L. M. et al. Risk factors for mucosal manifestation of American cutaneous leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, Inglaterra, v. 99, n.1, p. 55-61, 2005. Disponível em: <>. Acesso em: 29 jan. 2017.
Abstract: A case-comparison study was carried out to identify risk factors for mucosal manifestations of American cutaneous leishmaniasis (ACL) in southeast Brazil, using a series of 2820 patients, diagnosed with ACL between 1966 and 1999. The significant factors independently associated with mucosal leishmaniasis were: gender, age, nutritional status and length of disease. Mucosal leishmaniasis occurred 1.7 times more frequently among males than females; twice as often in individuals older than 22 years compared with the younger group; almost four times as often in individuals with severe malnutrition compared with those who were well nourished; and almost four times more frequently in individuals reporting the disease for more than 4 months compared with those reporting a shorter duration of the disease. Among individuals older than 22 years the risk of mucosal leishmaniasis increased significantly (from 1.9 to 9.6) as the nutritional status decreased, when compared with younger and well-nourished patients. The characteristics herein described and correlated with severe forms could be used as diagnostic markers as part of clinical screening in areas endemic for ACL.
ISSN: 1878-3503
Appears in Collections:DEMSC - Artigos publicados em periódicos

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