Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/7651
Title: Aerobic exercise and not a diet supplemented with jussara açaí (Euterpe edulis Martius) alters hepatic oxidative and inflammatory biomarkers in ApoE-deficient mice.
Authors: Castro, Cynthia Aparecida de
Natali, Antônio José
Cardoso, Luciana Marques
Machado, Alessandra Barbosa Ferreira
Novello, Alexandre Azevedo
Silva, Karina Ana da
Tafuri, Natalia Filard
Matta, Sergio Luis Pinto da
Pedrosa, Maria Lúcia
Peluzio, Maria do Carmo Gouveia
Keywords: Atherosclerosis
Anthocyanins
Antioxidants
Physical activity
Issue Date: 2014
Citation: CASTRO, C. A. et al. Aerobic exercise and not a diet supplemented with jussara açaí (Euterpe edulis Martius) alters hepatic oxidative and inflammatory biomarkers in ApoE-deficient mice. British Journal of Nutrition, v. 112, p. 285-294, 2014. Disponível em: <https://goo.gl/PruUsi>. Acesso em: 23 fev. 2017.
Abstract: The pulp of jussara açaí (Euterpe edulis Martius) fruit is rich in anthocyanins that exert antioxidant and anti-inflammatory effects similar to those exerted by aerobic exercise. In the present study, we investigated the effects of jussara açaí fruit pulp consumption, either alone or in combination with aerobic exercise, on the hepatic oxidative and inflammatory status of ApoE-deficient (ApoE 2/2) mice. Male mice were divided into four groups (control (C), control plus açaí, exercise plus açaí (EXA) and exercise (EX)) and fed the AIN-93M diet or the AIN-93M diet formulated to contain 2% freeze-dried açaí pulp. Mice in the EX and EXA groups were subjected to a progressive running programme (5 d/week, 60 min/d, 16 m/min) for 12 weeks. Mice that were made to exercise exhibited reduced (40·85 %; P,0·05) hepatic superoxide dismutase activity when compared with the C mice, independent of the açaí diet. Mice in the EX group exhibited a lower (42 %; P,0·05) mRNA expression of monocyte chemotactic protein-1 in the liver compared with the C mice. Mice in the EXA and EX groups had lower percentages of hepatic lipid droplets (70% and 56 %, respectively; P,0·05) when compared with the C mice. Mice in the EX group had smaller (58 %; P,0·05) area of lesions in the aorta when compared with the C mice. Serum lipid profile was not affected (P.0·05). In conclusion, aerobic exercise training rather than açaí fruit pulp consumption or a combination of both enhances the hepatic oxidative and inflammatory status of ApoE 2/2 mice.
URI: http://www.repositorio.ufop.br/handle/123456789/7651
metadata.dc.identifier.uri2: https://goo.gl/PruUsi
metadata.dc.identifier.doi: https://doi.org/10.1017/S000711451400083X
ISSN: 1475-2662
Appears in Collections:DECBI - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
ARTIGO_AerobicExerciseDiet.pdf310,38 kBAdobe PDFView/Open    Request a copy


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.