Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/762
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dc.contributor.authorCâmara, Diógenes Vadim-
dc.contributor.authorLemos, Virgínia Soares-
dc.contributor.authorSantos, Marcelo Henrique dos-
dc.contributor.authorNagem, Tanus Jorge-
dc.contributor.authorCôrtes, Steyner de França-
dc.date.accessioned2012-05-22T20:29:01Z-
dc.date.available2012-05-22T20:29:01Z-
dc.date.issued2010-
dc.identifier.citationCÂMARA, D. V. et al. Mechanism of the vasodilator effect of Euxanthone in rat small mesenteric arteries. Phytomedicine, v. 17, n. 8-9, p. 690-692, 2010. Disponível em: <https://www.sciencedirect.com/science/article/pii/S094471130900333X>. Acesso em: 22 maio 2012.pt_BR
dc.identifier.issn09447113-
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/762-
dc.description.abstractMechanism of the vasodilator effect of Euxanthone in rat small mesenteric arteries In the present work we investigated the mechanism involved in the vasodilator effect induced by euxanthone in rat small mesenteric arteries. We observed that euxanthone induced concentration dependent vasodilatation in arteries by a mechanism independent on the release of endothelial factors, such as nitric oxide (NO) and cyclooxygenase-derived factors. In addition our results also suggest that euxanthone induced its vasodilator effect through inhibition of calcium-sensitive mechanisms activated by protein kinase C, rather than by inhibition of contractions dependent on the release of the intracellular calcium stores or by inhibition of voltage-operated calcium channels.pt_BR
dc.language.isoen_USpt_BR
dc.subjectXanthonept_BR
dc.subjectProtein kinase Cpt_BR
dc.subjectResistance arterypt_BR
dc.subjectVasodilatationpt_BR
dc.titleMechanism of the vasodilator effect of Euxanthone in rat small mesenteric arteries.pt_BR
dc.typeArtigo publicado em periodicopt_BR
dc.rights.licenseO Periódico Phytomedicine concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3490231006877.-
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