Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/7423
Title: New aspects of the glucose activation of the H-ATPase in the yeast Saccharomyces cerevisae.
Authors: Souza, Marco Antônio Andrade de
Trópia, Maria José Magalhães
Brandão, Rogélio Lopes
Keywords: Signal transduction
Nutrient signalling
Issue Date: 2001
Citation: BRANDAO, R. L.; SOUZA, M. A. A.; TRÓPIA, M. J. M. New aspects of the glucose activation of the H-ATPase in the yeast Saccharomyces cerevisae. Microbiology, Inglaterra, v. 147, n.10, p. 2849-2855, 2001. Disponível em: <http://mic.microbiologyresearch.org/content/journal/micro/10.1099/00221287-147-10-2849#tab2>. Acesso em: 10 jan. 2017.
Abstract: The glucose-induced activation of plasma membrane ATPase from Saccharomyces cerevisiae was first described by Serrano in 1983. Many aspects of this signal transduction pathway are still obscure. In this paper, evidence is presented for the involvement of Snf3p as the glucose sensor related to this activation process. It is shown that, in addition to glucose detection by Snf3p, sugar transport is also necessary for activation of the ATPase. The participation of the G protein, Gpa2p, in transducing the internal signal (phosphorylated sugars) is also demonstrated. Moreover, the involvement of protein kinase C in the regulation of ATPase activity is confirmed. Finally, a model pathway is presented for sensing and transmission of the glucose activation signal of the yeast HM-ATPase.
URI: http://www.repositorio.ufop.br/handle/123456789/7423
metadata.dc.identifier.uri2: http://mic.microbiologyresearch.org/content/journal/micro/10.1099/00221287-147-10-2849#tab2
ISSN: 14652080
Appears in Collections:DEFAR - Artigos publicados em periódicos

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