Please use this identifier to cite or link to this item:
http://www.repositorio.ufop.br/jspui/handle/123456789/7383| Title: | A tetravalent dengue nanoparticle stimulates antibody production in mice. |
| Authors: | Silva, Elisângela F. Orsi, Mariana Andrade, Ângela Leão Domingues, Rosana Zacarias Silva, Breno de Mello Araújo, Helena Rocha Corrêa de Pimenta, Paulo Filemon Paolucci Diamond, Michael S. Rocha, Eliseu S. O. Kroon, Erna Geessien Malaquias, Luiz Cosme Cotta Coelho, Luiz Felipe Leomil |
| Keywords: | Inactivated Dengue vírus Nanoparticles Humoral response |
| Issue Date: | 2012 |
| Citation: | SILVA, E. F. et al. A tetravalent dengue nanoparticle stimulates antibody production in mice. Journal of Nanobiotechnology, v. 10, p. 13, 2012. Disponível em: <https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-10-13> Acesso em: 19 fev. 2017. |
| Abstract: | Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However, a subset of patients experiencing secondary infection with a different serotype progresses to the severe form of the disease, dengue hemorrhagic fever/dengue shock syndrome. Currently, there are no licensed vaccines or antiviral drugs to prevent or treat dengue infections. Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines. |
| URI: | http://www.repositorio.ufop.br/handle/123456789/7383 |
| metadata.dc.identifier.doi: | https://doi.org/10.1186/1477-3155-10-13 |
| ISSN: | 1477-3155 |
| metadata.dc.rights.license: | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: o próprio artigo. |
| Appears in Collections: | DECBI - Artigos publicados em periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ARTIGO_TetravalentDengueNanoparticle.pdf | 544,78 kB | Adobe PDF | View/Open |
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