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dc.contributor.authorReina, José Juan-
dc.contributor.authorMaio, Antonio Di-
dc.contributor.authorRamos Soriano, Javier-
dc.contributor.authorFigueiredo, Rute Cunha-
dc.contributor.authorRojo Marcos, Francisco Javier-
dc.identifier.citationLÓPEZ MARTÍN, J. J. et al. Rapid and efficient synthesis of α(1 – 2) mannobiosides. Organic & Biomolecular Chemistry, v. 14, p. 2873-2882, 2016. Disponível em: <>. Acesso em: 16 jun. 2016.pt_BR
dc.description.abstractα(1,2) mannobiosides with different substituents at the reducing end have been synthesized by a common strategy using benzoyls as the permanent protecting groups and an acetyl as the orthogonal protecting group at position C2 of the glycosyl acceptor. The new synthetic strategy has been performed remarkably reducing the number of purification steps, the time of synthesis (less than 72 hours) and improving the overall yield at least three times with respect to the best procedure described in the literature at the moment. Additionally, this protecting group strategy is compatible with the presence of azido groups and the use of Cu catalyzed azide alkyne cycloaddition (CuAAC) also called “click chemistry” for conjugating the α(1–2)mannobiosides to different scaffolds for the preparation of mannosyl multivalent systems.pt_BR
dc.titleRapid and efficient synthesis of α(1 – 2) mannobiosides.pt_BR
dc.typeArtigo publicado em periodicopt_BR
dc.rights.licenseThis article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Fonte: o próprio artigo.pt_BR
Appears in Collections:DEQUI - Artigos publicados em periódicos

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