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Title: Analysis of liver fragment subjected to autologous transplant at rat’s retroperitoneum.
Authors: Diniz, Mirla Fiuza
Siqueira, Sávio Lana
Baumfeld, Tiago Soares
Pereira, Luis Felipe Cintra
Moreira, Filipe Garcia
Ribeiro, Gustavo Meirelles
Souza, Iure Kalinine Ferraz de
Keywords: Hepatic regeneration
Experimental surgery
Issue Date: 2015
Citation: DINIZ, M. F. et al. Analysis of liver fragment subjected to autologous transplant at rat’s retroperitoneum. The Journal of Surgical Research (Print), v. 199, p. 407-411, 2015. Disponível em: <>. Acesso em: 16 jun. 2016.
Abstract: Background: To investigate the regeneration process of autologous implants of liver on the retroperitoneum. Methods: Thirty male Fisher rats were used divided in to group 1 (G1): studied 60 d after surgery; group 2 (G2): studied 90 d after surgery; group 3 (G3): studied 180 d after surgery; and group C (GC): animals without surgery. Hepatic fragment was processed for histologic and biochemical analysis. Results: There was inflammatory infiltrate, diffuse hydropic degeneration, necrosis, and moderate fibrosis that reduced in direct relation to the postsurgical time. The concentration of albuminwas differentbetweenGCandG1 and betweenG1 andG3 (P¼0.0007).The Catalase (CAT) was related to the time of surgery with GC being different when compared with G1, G2, and G3 (P < 0.0001). The oxidative stress measured through the thiobarbituric acid reactive substances lipid peroxidation was different between the GC and the G2 groups (P ¼ 0.0381). Conclusions: The analysis made showed hepatic regeneration in the fragment subjected to autologous transplant at the retroperitoneum
ISSN: 0022-4804
metadata.dc.rights.license: O periódico Journal of Surgical Research concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3894850393265.
Appears in Collections:DECGP - Artigos publicados em periódicos

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