Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/6008
Title: Salacia crassifolia (Celastraceae) : chemical constituents and antimicrobial activity.
Authors: Rodrigues, Vanessa Gregório
Duarte, Lucienir Pains
Silva, Roqueline Rodrigues
Silva, Grácia Divina de Fátima
Simões, Maria O. Mercadante
Takahashi, Jacqueline Aparecida
Matildes, Bibiane Lindsay Guimarães
Fonseca, Thaisa Helena Silva
Gomes, Maria Aparecida
Vieira Filho, Sidney Augusto
Issue Date: 2015
Citation: RODRIGUES, V. G. et al. Salacia crassifolia (Celastraceae) : chemical constituents and antimicrobial activity. Química Nova, v. 2, p. 237-242, 2015. Disponível em: <http://www.scielo.br/scielo.php?pid=S0100-40422015000200237&script=sci_arttext>. Acesso em: 15 out. 2015.
Abstract: The phytochemical study of hexane extract from leaves of Salacia crassifolia resulted in the isolation of 3β-palmitoxy-urs-12-ene, 3-oxofriedelane, 3β-hydroxyfriedelane, 3-oxo-28-hydroxyfriedelane, 3-oxo-29-hydroxyfriedelane, 28,29-dihydroxyfriedelan-3-one, 3,4-seco-friedelan-3-oic acid, 3β-hydroxy-olean-9(11):12-diene and the mixture of α-amirin and β-amirin. β-sitosterol, the polymer gutta-percha, squalene and eicosanoic acid were also isolated. The chemical structures of these constituents were established by IR, 1H and 13C NMR spectral data. Crude extracts and the triterpenes were tested against Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis and no activity was observed under the in vitro assay conditions. The hexane, chloroform, ethyl acetate and ethanol crude extracts, and the constituent 3,4-seco-friedelan-3-oic acid and 28,29-dihydroxyfriedelan-3-one showed in vitro antimicrobial activity against Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Streptococcus sanguinis and Candida albicans.
URI: http://www.repositorio.ufop.br/handle/123456789/6008
ISSN: 16787064
metadata.dc.rights.license: A Sociedade Brasileira de Química dá permissão à UFOP para reproduzir no RI/UFOP, uma cópia em formato eletrônico dos artigos completos, sem nenhuma edição e/ou modificação, publicados na revista Química Nova, que tenham como autores seus alunos e/ou professores. Fonte: Email do editor de 17 set. 2013.
Appears in Collections:DEFAR - Artigos publicados em periódicos

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