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http://www.repositorio.ufop.br/jspui/handle/123456789/5147| Title: | Chemical constituents from branches of Maytenus gonoclada (Celastraceae) and evaluation of antimicrobial activity. |
| Authors: | Silva, Fernando César Duarte, Lucienir Pains Silva, Grácia Divina de Fátima Vieira Filho, Sidney Augusto Lula, Ivana Silva Takahashi, Jacqueline Aparecida Sallum, William S. T. |
| Keywords: | Maytenus gonoclada Dihydroxyfriedelane Antimicrobial activity |
| Issue Date: | 2011 |
| Citation: | SILVA, F. C. et al. Chemical constituents from branches of Maytenus gonoclada (Celastraceae) and evaluation of antimicrobial activity. Journal of the Brazilian Chemical Society, v. 22, p. 943-949, 2011. Disponível em: <http://www.scielo.br/scielo.php?pid=S0103-50532011000500018&script=sci_arttext> Acesso em: 20 ago. 2014. |
| Abstract: | Seis triterpenos pentacíclicos isolados dos galhos de Maytenus gonoclada (Celastraceae), incluindo todos os dados de RMN do novo composto 3-oxo-12α,29-diidroxifriedelano são aqui relatados. A estereoquímica do novo friedelano foi estabelecida por dados de RMN bidimensional (HSQC, HMBC e NOESY), e sua massa molecular confirmada por espectrometria de massas (ESI). Testes de atividade antimicrobiana usando método de difusão em disco e de macrodiluição foram realizados contra as bactérias Escherichia coli, Citrobacter freundii e Bacillus cereus, e contra o fungo Candida albicans. O triterpeno 3-oxo-12a-hidroxifriedelano mostrou resultado positivo contra C. albicans. |
| metadata.dc.description.abstracten: | Six pentacyclic triterpenes were isolated from branches of Maytenus gonoclada (Celastraceae) and all NMR data of a new compound 3-oxo-12α,29-dihydroxyfriedelane are herein reported. The stereochemistry of the new friedelane was established by bidimensional NMR (HSQC, HMBC and NOESY) data, and its molecular weight confirmed by ESI mass spectrometry. Antimicrobial activity assays using the method of disk diffusion and macrodilution were carried out against the bacteria Escherichia coli, Citrobacter freundii, and Bacillus cereus, and against the fungi Candida albicans. The triterpene 3-oxo-12a-hydroxyfriedelane showed positive result against C. albicans. |
| URI: | http://www.repositorio.ufop.br/handle/123456789/5147 |
| metadata.dc.identifier.doi: | http://dx.doi.org/10.1590/S0103-50532011000500018 |
| ISSN: | 1678-4790 |
| metadata.dc.rights.license: | O periódico Journal of the Brazilian Chemical Society permite que a UFOP deposite uma cópia em formato eletrônico dos artigos de seus alunos e professores publicados neste periódico no Repositório Institucional. Contato via email em 13 set. 2013. |
| Appears in Collections: | DEFAR - Artigos publicados em periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ARTIGO_ChemicalConstituentsBranches.pdf | 1,94 MB | Adobe PDF | View/Open |
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