Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/4979
Title: Facile synthesis of symmetrical 3,3-diarylacrylates by a Heck-Matsuda reaction : an expedient route to biologically active indanones.
Authors: Taylor, Jason Guy
Ribeiro, Rodrigo da Silva
Correia, Carlos Roque Duarte
Keywords: Arenediazonium tetrafluoroborates
Heck-Matsuda
Arylation
Indanones
Palladium
Issue Date: 2011
Citation: TAYLOR, J. G.; RIBEIRO, R. da S.; CORREIA, C. R. D. Facile synthesis of symmetrical 3,3-diarylacrylates by a Heck-Matsuda reaction: an expedient route to biologically active indanones. Tetrahedron Letters, v. 52, p. 3861-3864, 2011. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0040403911007763>. Acesso em: 02 fev. 2015.
Abstract: A simple and straightforward synthesis of symmetrical 3,3-diarylacrylates based on a Heck-Matsuda reaction of arenediazonium salts bearing electron-donating groups with methylacrylates is described. The reaction employs Pd(OAc)2 as catalyst and goes to completion within 1 h affording the corresponding unsaturated diaryl esters in good to high yields. This method permitted the expeditious and efficient synthesis of the anticancer 3-arylindanone 5 in two operative steps in 43% overall yield.
URI: http://www.repositorio.ufop.br/handle/123456789/4979
metadata.dc.identifier.doi: https://doi.org/10.1016/j.tetlet.2011.05.039
ISSN: 0040-4039
metadata.dc.rights.license: O periódico Tetrahedron Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3581340458166.
Appears in Collections:DEQUI - Artigos publicados em periódicos

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