Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/3864
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDuarte, Lucienir Pains-
dc.contributor.authorVieira Filho, Sidney Augusto-
dc.contributor.authorSilva, Grácia Divina de Fátima-
dc.contributor.authorSousa, José Rego de-
dc.contributor.authorPinto, Artur da Silveira-
dc.date.accessioned2014-11-14T19:04:07Z-
dc.date.available2014-11-14T19:04:07Z-
dc.date.issued2002-
dc.identifier.citationDUARTE, L. P. et al. Anti-trypanosomal activity of pentacyclic triterpenes isolated from Austroplenckia populnea (Celastraceae). Revista do Instituto de Medicina Tropical de São Paulo, São Paulo, v. 44, n.2, p. 109-112, 2002. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&nrm=iso&lng=pt&tlng=pt&pid=S0036-46652002000200010>. Acesso em: 20 ago. 2014.pt_BR
dc.identifier.issn0036-4665-
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/3864-
dc.description.abstractFour pentacyclic triterpenes isolated from Austroplenckia populnea and four compounds of known anti T. cruzi or anti-malarial activity were tested. Of those triterpenes tested 20_-hydroxy-tingenone showed high activity, epikatonic acid was less active, while populnilic and populninic acids were inactive against the trypanosome of the subgenus Schizotrypanum tested. Benzonidazole, nifurtimox, ketoconazole and primaquine presented a remarkable dose-dependent inhibitory effect reaching practically to a total growth inhibition of the parasite at the end of incubation time. The trypanosome tested appear to be a suitable model for preliminary screen for anti T. (S.) cruzi compounds.pt_BR
dc.language.isoen_USpt_BR
dc.subjectAustroplenckia populneapt_BR
dc.subjectPentacyclic triterpenespt_BR
dc.subjectAnti-trypanosomal activitypt_BR
dc.subjectGrowth inhibitionpt_BR
dc.titleAnti-trypanosomal activity of pentacyclic triterpenes isolated from Austroplenckia populnea (Celastraceae).pt_BR
dc.typeArtigo publicado em periodicopt_BR
dc.rights.licenseA Revista do Instituto de Medicina Tropical de São Paulo permite que o Repositório Institucional da Universidade Federal de Ouro Preto (UFOP) deposite uma cópia eletrônica dos artigos publicados por esse periódico  em que ao menos um dos autores faça parte da comunidade cientifica da UFOP. Fonte: Licença concedida por email enviado no dia 06/12/2013.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1590/S0036-46652002000200010-
Appears in Collections:DEFAR - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
ARTIGO_AntiTrypanosomalActivity.pdf56,51 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.