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Title: Evaluation of antimicrobial activity and toxic potential of extracts and triterpenes isolated from Maytenus imbricata.
Authors: Rodrigues, Vanessa Gregório
Duarte, Lucienir Pains
Silva, Grácia Divina de Fátima
Silva, Fernando César
Góes, Jefferson Vieira de
Takahashi, Jacqueline Aparecida
Pimenta, Lúcia Pinheiro Santos
Vieira Filho, Sidney Augusto
Keywords: Maytenus imbricata
Pentacyclic triterpenes
Issue Date: 2012
Citation: RODRIGUES, V. G. et al. Evaluation of antimicrobial activity and toxic potential of extracts and triterpenes isolated from Maytenus imbricata. Química Nova, v. 35, p. 1375-1380, 2012. Disponível em: <>. Acesso em: 20 ago. 2014.
Abstract: The phytochemical study of hexane/ethyl ether (1:1) extract of the roots of M. imbricata, Celastraceae, resulted in the isolation and characterization of six known triterpenes: 11α-hydroxylup-20(29)-en-3-one, previously isolated from this species besides, 3β,11α- di-hydroxylup-20(29)-ene, 3,7-dioxofriedelane, 3-oxo-29-hydroxyfriedelane, tingenone and 6-oxo-tingenol. The chemical structures of these triterpenes were established by spectrometric data (IR, 1H and 13C NMR) and through comparison with literature data. The hexane/ethyl ether (1:1), ethyl acetate and methanol extracts, and 11α-hydroxylup-20(29)-en-3-one, tingenone and 6-oxo-tingenol, showed antimicrobial properties on in vitro assays. All extracts and triterpenes, except 3β,11α-di-hydroxylup-20(29)-ene, presented toxicity demonstrated by the larvicidal effect test using Artemia salina.
ISSN: 1678-7064
metadata.dc.rights.license: A Sociedade Brasileira de Química dá permissão à UFOP para reproduzir no RI/UFOP, uma cópia em formato eletrônico dos artigos completos, sem nenhuma edição e/ou modificação, publicados na revista Química Nova, que tenham como autores seus alunos e/ou professores. Fonte: Email do editor de 17 set. 2013.
Appears in Collections:DEFAR - Artigos publicados em periódicos

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