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Title: Triglyceride-glucose index is associated with poor sleep quality in apparently healthy subjects : a cross-sectional study.
Authors: Avelino, Daniela Carolina
Silva, Alessandra da
Chaves, Larissa Oliveira
Carraro, Júlia Cristina Cardoso
Vidigal, Fernanda de Carvalho
Bressan, Josefina
Keywords: Cardiometabolic risk
Insulin resistance
ROC curve
Sleep quality
TyG index
Issue Date: 2022
Citation: AVELINO, D. C. et al. Triglyceride-glucose index is associated with poor sleep quality in apparently healthy subjects: a cross-sectional study. Archives of Endocrinology Metabolism, v. 67, n. 1, p. 73-91, 2022. Disponível em: <>. Acesso em: 01 ago. 2023.
Abstract: Objectives: We aimed to evaluate the association between the triglyceride glucose index (TyG index) and sleep quality and to establish a cut-off value for the TyG index based on the prevalence of subjects with insulin resistance (IR). Materials and methods: This cross-sectional study involved Brazilian health professionals (20-59 years). A total of 138 subjects answered the Pittsburgh Sleep Quality questionnaire to evaluate sleep quality. They were categorized into two groups: good sleep quality (global score ≤ 5 points) and poor sleep quality (global score ≥ 6 points). Also, we classified the subjects as having a high (>8.08 or >4.38) or low TyG index (≤8.08 or ≤4.38). Results: The majority of the subjects (70%) with high TyG index values (>8.08 or >4.38) reported poor sleep quality (p ≤ 0.001). Those with poor sleep quality had a 1.44-fold higher prevalence of IR (TyG index >8.08 or >4.38) compared to those with good sleep quality, regardless of sex, total cholesterol, LDL/HDL ratio, insulin, complement C3, CRP, and adiponectin (p ≤ 0.001). Conclusion: Our data showed a positive and significant association between the TyG index and poor sleep quality. Thus, these findings support the association between poor sleep quality and IR.
ISSN: 2359-4292
metadata.dc.rights.license: This is an open access article distributed under the terms of the Creative Commons license. Fonte: PDF do artigo.
Appears in Collections:DENCS - Artigos publicados em periódicos

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