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Título: | Epigenetic markers associated with schistosomiasis. |
Autor(es): | Assenço, Regina Aparecida Gomes Mota, Ester Alves Oliveira, Victor Fernandes de Borges, William de Castro Cota, Renata Guerra de Sá |
Palavras-chave: | DNA methylation Histone modification miRNAs |
Data do documento: | 2021 |
Referência: | ASSENÇO, R. A. G. et al. Epigenetic markers associated with schistosomiasis. Helminthologia, v. 58, p. 28-40, 2021. Disponível em: <https://www.sciendo.com/article/10.2478/helm-2021-0009>. Acesso em: 10 jun. 2021. |
Resumo: | It is important to consider the use of the epigenome as source of complementary data for genome knowledge, which is suitable for the diagnosis of schistosomiasis. Usually, a laboratory diagnosis of schistosomiasis is performed by means of 1. Egg detection in the stool or urine by microscopy remains with limited sensitivity; 2. Immunological screening, in which positivity persists after treatment, and 3. Molecular appraisals prevail over the disadvantages of the currently used methods. In this sense, molecular methodologies are being developed based on epigenetic biomarkers, aiming to improve the diagnosis of the disease and clinical treatment as early as possible to prevent the occurrence of serious liver damage. |
URI: | http://www.repositorio.ufop.br/jspui/handle/123456789/14016 |
Link para o artigo: | https://www.sciendo.com/article/10.2478/helm-2021-0009 |
DOI: | https://doi.org/10.2478/helm-2021-0009 |
ISSN: | 1336-9083 |
Licença: | This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. Fonte: Helminthologia. https://www.sciendo.com/article/10.2478/helm-2021-0009>. Acesso em: 10 nov. 2021. |
Aparece nas coleções: | DECBI - Artigos publicados em periódicos |
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ARTIGO_EpigeneticMarkersAssociated.pdf | 2,83 MB | Adobe PDF | Visualizar/Abrir |
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