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http://www.repositorio.ufop.br/jspui/handle/123456789/11225
Title: | Determination of nine pharmaceutical active compounds in surface waters from Paraopeba River Basin in Brazil by LTPE-HPLC-ESI-MS/MS. |
Authors: | Barros, André Luis Corrêa de Schmidt, Felix Florian Aquino, Sergio Francisco de Afonso, Robson José de Cássia Franco |
Keywords: | Low-temperature partitioning extraction |
Issue Date: | 2018 |
Citation: | BARROS, A. L. C. de et al. Determination of nine pharmaceutical active compounds in surface waters from Paraopeba River Basin in Brazil by LTPE-HPLC-ESI-MS/MS. Environmental Science and Pollution Research, v. 25, n. 20, p. 19962–19974, jul. 2018. Disponível em: <https://link.springer.com/article/10.1007%2Fs11356-018-2123-y>. Acesso em: 7 mar. 2019. |
Abstract: | A simple, inexpensive, versatile, and environment-friendly extraction method, using low-temperature partitioning extraction (LTPE), was validated to quantify pharmaceutical-active compounds (PhACs) in surface water samples by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). The PhACs analyzed were acetaminophen, bezafibrate, diclofenac, diltiazem, fluconazole, linezolid, miconazole, ondansetron hydrochloride, and trimethoprim. The detection and quantification limits ranged from 0.15 to 12.30 ng L−1 and 0.43 to 40.60 ng L−1, respectively. Recovery rates ranged from 46 to 135%, and relative standard deviation (RSD%) varied between 0.49 and 6.13%. This method was applied to monitor water contamination by PhACs in the Paraopeba River Basin (PRB), Minas Gerais state, Brazil. All PhACs, except linezolid which was not detected, were found in PRB water samples in concentrations that ranged from 2.6 ng L−1 to 2.62 μg L−1. |
URI: | http://www.repositorio.ufop.br/handle/123456789/11225 |
metadata.dc.identifier.uri2: | https://link.springer.com/article/10.1007%2Fs11356-018-2123-y |
metadata.dc.identifier.doi: | https://doi.org/10.1007/s11356-018-2123-y |
ISSN: | 1614-7499 |
Appears in Collections: | DEQUI - Artigos publicados em periódicos |
Files in This Item:
File | Description | Size | Format | |
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ARTIGO_DeterminationNinePharmaceutical.pdf Restricted Access | 2,25 MB | Adobe PDF | View/Open |
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