Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/handle/123456789/11225
Title: Determination of nine pharmaceutical active compounds in surface waters from Paraopeba River Basin in Brazil by LTPE-HPLC-ESI-MS/MS.
Authors: Barros, André Luis Corrêa de
Schmidt, Felix Florian
Aquino, Sergio Francisco de
Afonso, Robson José de Cássia Franco
Keywords: Low-temperature partitioning extraction
Issue Date: 2018
Citation: BARROS, A. L. C. de et al. Determination of nine pharmaceutical active compounds in surface waters from Paraopeba River Basin in Brazil by LTPE-HPLC-ESI-MS/MS. Environmental Science and Pollution Research, v. 25, n. 20, p. 19962–19974, jul. 2018. Disponível em: <https://link.springer.com/article/10.1007%2Fs11356-018-2123-y>. Acesso em: 7 mar. 2019.
Abstract: A simple, inexpensive, versatile, and environment-friendly extraction method, using low-temperature partitioning extraction (LTPE), was validated to quantify pharmaceutical-active compounds (PhACs) in surface water samples by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). The PhACs analyzed were acetaminophen, bezafibrate, diclofenac, diltiazem, fluconazole, linezolid, miconazole, ondansetron hydrochloride, and trimethoprim. The detection and quantification limits ranged from 0.15 to 12.30 ng L−1 and 0.43 to 40.60 ng L−1, respectively. Recovery rates ranged from 46 to 135%, and relative standard deviation (RSD%) varied between 0.49 and 6.13%. This method was applied to monitor water contamination by PhACs in the Paraopeba River Basin (PRB), Minas Gerais state, Brazil. All PhACs, except linezolid which was not detected, were found in PRB water samples in concentrations that ranged from 2.6 ng L−1 to 2.62 μg L−1.
URI: http://www.repositorio.ufop.br/handle/123456789/11225
metadata.dc.identifier.uri2: https://link.springer.com/article/10.1007%2Fs11356-018-2123-y
metadata.dc.identifier.doi: https://doi.org/10.1007/s11356-018-2123-y
ISSN: 1614-7499
Appears in Collections:DEQUI - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
ARTIGO_DeterminationNinePharmaceutical.pdf2,25 MBAdobe PDFView/Open    Request a copy


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.