Please use this identifier to cite or link to this item:
Title: Exercise training improves quality of life in women with subclinical hypothyroidism : a randomized clinical trial.
Authors: Werneck, Francisco Zacaron
Coelho, Emerson Filipino
Almas, Saulo Peters
Garcia, Marília Mendes do Nascimento
Bonfante, Heloina Lamha Machado
Lima, Jorge Roberto Perrout de
Vigário, Patrícia dos Santos
Mainenti, Miriam Raquel Meira
Teixeira, Patrícia de Fátima dos Santos
Vaisman, Mário
Keywords: Quality of life
Functional capacity
Issue Date: 2018
Citation: WERNECK, F. Z. et al. Exercise training improves quality of life in women with subclinical hypothyroidism : a randomized clinical trial. Archives of Endocrinology and Metabolism, São Paulo, v. 2, n. 5, p. 530-536, out. 2018. Disponível em: <>. Acesso em: 20 fev. 2019.
Abstract: Objective: The aim was to evaluate the quality of life (HRQoL) in women with subclinical hypothyroidism (sHT) after 16 weeks of endurance training. Subjects and methods: In the first phase, a cross-sectional study was conducted in which 22 women with sHT (median age: 41.5 (interquartile range: 17.5) years, body mass index: 26.2 (8.7) kg/m2 , thyroid stimulating hormone > 4.94 mIU/L and free thyroxine between 0.8 and 1.3 ng/dL were compared to a group of 33 euthyroid women concerned to HRQoL. In the second phase, a randomized clinical trial was conducted where only women with sHT were randomly divided into two groups: sHT-Tr (n = 10) – participants that performed an exercise program – and sHT-Sed (n = 10) – controls. Exercise training consisted of 60 minutes of aerobic activities (bike and treadmill), three times a week, for 16 weeks. The HRQoL was assessed by the SF-36 questionnaire in the early and at the end of four months. Results: Women with sHT had lower scores on functional capacity domain in relation to the euthyroid ones (77.0 ± 23.0 vs. 88.8 ± 14.6; p = 0.020). The sHT-Tr group improved functional capacity, general health, emotional aspects, mental and physical component of HRQoL after training period, while the sHT-Sed group showed no significant changes. Conclusion: After 16 weeks of aerobic exercise training, there were remarkable improvements in HRQoL in women with sHT.
ISSN: 0004-2730
metadata.dc.rights.license: Todo o conteúdo do periódico Arquivos Brasileiros de Endocrinologia e Metabologia, exceto onde identificado, está licenciado sob uma licença Creative Commons 4.0 que permite copiar, distribuir e transmitir o trabalho em qualquer suporte ou formato desde que sejam citados o autor e o licenciante. Fonte: Arquivos Brasileiros de Endocrinologia e Metabologia <>. Acesso em: 17 out. 2016.
Appears in Collections:DEEFD - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
ARTIGO_ExerciseTrainingImproves.pdf144,41 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.