Please use this identifier to cite or link to this item: http://www.repositorio.ufop.br/jspui/handle/123456789/10840
Title: Performance of rapid prescreening and 100% rapid review as internal quality control methods for cervical cytopathology.
Authors: Tobias, Alessandra Hermógenes Gomes
Vitalino, Aline Costa
Rezende, Mariana Trevisan
Oliveira, Renata Rocha e Rezende
Vital, Wendel Coura
Amaral, Rita Goreti
Carneiro, Cláudia Martins
Keywords: Cervical cancer
Gynaecological cytology
Sensitivity
Issue Date: 2018
Citation: TOBIAS, A. H. G. et al. Performance of rapid prescreening and 100% rapid review as internal quality control methods for cervical cytopathology. Cytopathology, v. 29, n. 5, p. 428-435, out. 2018. Disponível em: <https://onlinelibrary.wiley.com/doi/full/10.1111/cyt.12599>. Acesso em: 21 fev. 2019.
Abstract: Background An objective of quality control for cervical cytopathology is reducing high rates of false‐negative results of laboratory tests. Therefore, methods to review smears such as rapid prescreening and 100% rapid review, which have shown better performance detecting false‐negative results, have been widely used. The performance of rapid prescreening and the performance of 100% rapid review as internal quality control methods for cervical cytology examinations were evaluated. Methods For 24 months, 9318 conventional cervical cytology smears underwent rapid prescreening and routine screening. The 100% rapid review method was performed for 8244 smears classified as negative during routine screening. Any discordant results underwent detailed review to define the final diagnosis. This was considered the gold standard for evaluating the performance of rapid prescreening and 100% rapid review. Results Routine screening showed increases of 13.3% and 11.5% in the detection of abnormal smears with rapid prescreening and 100% rapid review, respectively. The relative percentage variation showed a 38.1% increase in the diagnosis of atypical squamous cells of undetermined significance with routine screening and rapid prescreening and a 12.5% increase in the diagnosis of atypical squamous cells, cannot exclude high‐grade squamous intraepithelial lesion with both rapid prescreening and 100% rapid review. Sensitivity rates of rapid prescreening and routine screening were 48.2% and 83.2%, respectively. Sensitivity rates of rapid prescreening and 100% rapid review were 65.7% and 57.8%, respectively, for detecting false‐negative results. Conclusions Inclusion of rapid prescreening and/or 100% rapid review improved the diagnostic sensitivity of the cervical cytology examination and reduced false‐negative results of routine screening and can provide good quality control.
URI: http://www.repositorio.ufop.br/handle/123456789/10840
metadata.dc.identifier.uri2: https://onlinelibrary.wiley.com/doi/full/10.1111/cyt.12599
ISSN: 13652303
Appears in Collections:DEACL - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
ARTIGO_PerformanceRapidPrescreening.pdf
  Restricted Access
173,35 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.