Use este identificador para citar ou linkar para este item:
http://www.repositorio.ufop.br/jspui/handle/123456789/17967
Título: | Cardiac changes in spontaneously hypertensive rats : modulation by aerobic exercise. |
Autor(es): | Teles, Maria Cecília Portes, Alexandre Martins Oliveira Coelho, Bianca Iara Campos Resende, Letícia Teresinha Isoldi, Mauro César |
Palavras-chave: | Hypertension Aerobic exercise Oxidative stress Inflammation Cardiac hypertrophy |
Data do documento: | 2023 |
Referência: | TELES, M. C. et al. Cardiac changes in spontaneously hypertensive rats : modulation by aerobic exercise. Progress in Biophysics & Molecular Biology, v. 175, p. 109-124, jan. 2023. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0079610722001171>. Acesso em: 01 ago. 2023. |
Resumo: | Systemic arterial hypertension is a multifactorial clinical condition characterized by high and sustained levels of blood pressure. For a better understanding of the pathophysiology of hypertension, studies are conducted with spontaneously hypertensive animals, which allow the investigation of physiological changes that in most cases cannot be studied in humans. In these animals, myocardial remodeling, increased pro-inflammatory markers, redox imbalance and contractile dysfunctions that lead to changes in cardiac function can be observed. However, it can be inferring that aerobic training improves cardiac function and cardiomyocyte contractility, in addition to controlling inflammation and reducing oxidative stress in cardiac muscle, despite this, the precise mechanisms by which physical exercise improves cardiovascular control are not fully understood. In this review, we provide an overview of the pathophysiological changes that affect the heart of spontaneously hypertensive animals and their modulation by aerobic exercise. |
URI: | http://www.repositorio.ufop.br/jspui/handle/123456789/17967 |
Link para o artigo: | https://www.sciencedirect.com/science/article/pii/S0079610722001171 |
DOI: | https://doi.org/10.1016/j.pbiomolbio.2022.11.001 |
ISSN: | 0079-6107 |
Aparece nas coleções: | DECBI - Artigos publicados em periódicos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
---|---|---|---|---|
ARTIGO_CardiacChangesSpontaneously.pdf Restricted Access | 2,21 MB | Adobe PDF | Visualizar/Abrir |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.