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http://www.repositorio.ufop.br/jspui/handle/123456789/9928| Título: | Antibacterial activity of extract and fractions from branches of Protium spruceanum and cytotoxicity on fibroblasts. |
| Autor(es): | Amparo, Tatiane Roquete Rodrigues, Ivanildes Vasconcelos Seibert, Janaína Brandão Souza, Rafaella Hilda Zaniti Oliveira, Amanda Ribeiro de Cabral, Vivette Appolinário Rodrigues Vieira, Paula Melo de Abreu Brandão, Geraldo Célio Okuma, Adriana Akemi Vieira Filho, Sidney Augusto Teixeira, Luiz Fernando de Medeiros Souza, Gustavo Henrique Bianco de |
| Palavras-chave: | Protium spruceanum Cytotoxicity Antbacterial activity |
| Data do documento: | 2017 |
| Referência: | AMPARO, T. R. et al. Antibacterial activity of extract and fractions from branches of Protium spruceanum and cytotoxicity on fibroblasts. Natural Product Research, v. 01, p. 1-5, 2017. Disponível em: <https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1354182?journalCode=gnpl20>. Acesso em: 05 abr. 2018. |
| Resumo: | The crude ethanol extract (CEE) and fractions from branches of Protium spruceanum were subjected to antibacterial and cytotoxicity assays. Compounds of the most active fraction were identified by GC-MS and LC-MS. CEE was active against 19 bacteria and the ethyl acetate fraction (EAF) showed the lowest minimum bactericidal concentration (MBC 0.3–80.0 mg/mL). Through time-kill assay was observed that EAF induced rapid bactericidal effect against Staphylococcus saprophyticus. The cytotoxicity tests against L929 fibroblasts showed great potential of EAF on the treatment of infections caused by five bacteria (MBC < IC50). The results provide in vitro scientific support to the possible application of branches of P. spruceanum as antimicrobial agent that may contribute for treatment of infections. |
| URI: | http://www.repositorio.ufop.br/handle/123456789/9928 |
| Link para o artigo: | https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1354182?journalCode=gnpl20 |
| ISSN: | 14786427 |
| Aparece nas coleções: | DEFAR - Artigos publicados em periódicos |
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| Arquivo | Descrição | Tamanho | Formato | |
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| ARTIGO_AntibacterialActivityExtract.pdf Restricted Access | 826,46 kB | Adobe PDF | Visualizar/Abrir |
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