Current strategies for diagnosis of paracoccidioidomycosis and prospects of methods based on gold nanoparticles.
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2016
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Resumo
Paracoccidioidomycosis (PCM) is a human systemic granulomatous mycosis caused by
thermodimorphic fungi from Paracoccidioides genus. The disease is prevalent in Latin America
and triggers a serious clinical condition. Consequently, rapid diagnosis and treatment are
crucial to prevent progression of the disease, which can result in death. Currently, there are
several established methods for PCM diagnosis. However, many of these tests still present
challenges in terms of cost, accessibility and efficiency. In this scenario, gold nanoparticles
represent a promising alternative since they have particular optical and electronic properties,
which allow its use for biomolecules detection. This review will briefly present techniques
available for PCM diagnosis and the perspectives of implementation of gold nanoparticles
for diagnosis of this mycosis.
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Gold nanospheres, Paracoccidioides brasiliensis, Paracoccidioides lutzii
Citação
FERREIRA, C. S. et al. Current strategies for diagnosis of paracoccidioidomycosis and prospects of methods based on gold nanoparticles. Future Microbiology, v. 11, p. 973-985, 2016. Disponível em: <https://www.futuremedicine.com/doi/10.2217/fmb-2016-0062>. Acesso em: 15 set. 2017.