Molecular mechanisms of myocarditis caused by Trypanosoma cruzi.
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Data
2015
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Resumo
American trypanosomiasis, or Chagas disease, is a lifelong and persistent infection caused by the
protozoan Trypanosoma cruzi and is the most significant cause of morbidity and mortality in South and
Central America. Owing to immigration and additional risks from blood transfusion and organ
transplantation, the number of reported cases of Chagas disease has increased recently in Europe and the
USA. The disease is caused by a moderate to intense lasting inflammatory response that triggers local
expression of inflammatory mediators and activates and recruits leukocytes to various tissues to eliminate
the parasites.
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Chagas disease, Immunoregulation, Myocarditis, Trypanosoma cruzi
Citação
ESPER, L. et al. Molecular mechanisms of myocarditis caused by Trypanosoma cruzi. Current Opinion in Infectious Diseases, v. 28, p. 246-252, 2015. Disponível em:<http://insights.ovid.com/pubmed?pmid=25887609> . Acesso em: 16 jun. 2017.