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dc.contributor.authorFreitas, José Cláudio Carneiro de-
dc.contributor.authorLopes Neto, Belarmino Eugênio-
dc.contributor.authorAbreu, Cyntia Rafaelle Amaral de-
dc.contributor.authorVital, Wendel Coura-
dc.contributor.authorBraga, Samuel Leôncio-
dc.contributor.authorReis, Alexandre Barbosa-
dc.contributor.authorPinheiro, Diana Célia Sousa Nunes-
dc.date.accessioned2015-01-19T16:34:58Z-
dc.date.available2015-01-19T16:34:58Z-
dc.date.issued2012-
dc.identifier.citationFREITAS, J.C. C. de et al. Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis. Research in Veterinary Science, v. 93, p. 705-709, 2012. Disponível em: <http://www.ncbi.nlm.nih.gov/pubmed/22226072>. Acesso em: 13 ago. 2014.pt_BR
dc.identifier.issn00345288-
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/4259-
dc.description.abstractThis research investigated the profile of anti-Leishmania antibodies in different clinical forms of canine visceral leishmaniasis (CVL). Naturally infected dogs were divided into two groups: subclinical dogs (SD, n = 10) and clinical dogs (CD, n = 68). Non-infected dogs (ND, n = 7) comprised the negative control group. The humoral response was evaluated by the profile of total IgG, IgG1, IgG2, IgM, IgA and IgE, determined by ELISA. Infected animals showed increased levels of total IgG, IgA and IgE in addition to IgG1 and IgG2 in groups SD and CD, when compared with group ND. Furthermore, it was observed that IgG2 and IgM were correlated with symptomatology, while total IgG, IgG1 and IgA were negatively correlated and IgE showed no correlation. It follows that serum levels of IgG2 anti-Leishmania are correlated with typical clinical signs of disease. Furthermore the determination of specific anti-Leishmania antibodies could be an important tool in monitoring CVL clinical picture.pt_BR
dc.language.isoen_USpt_BR
dc.subjectLeishmania antibodiespt_BR
dc.subjectCanine visceral leishmaniasispt_BR
dc.subjectClinical picturespt_BR
dc.subjectLeishmania chagasipt_BR
dc.titleProfile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.pt_BR
dc.typeArtigo publicado em periodicopt_BR
dc.rights.licenseO Periódico Research in Veterinary Science concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3442010848687.pt_BR
Aparece nas coleções:DEACL - Artigos publicados em periódicos 2

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