Use este identificador para citar ou linkar para este item:
http://www.repositorio.ufop.br/jspui/handle/123456789/17944
Título: | Thermoregulatory responses, heart rate, and the susceptibility to anxiety in obese animals subjected to stress. |
Autor(es): | Santos, Áquila Rodrigues Costa Abreu, Aline Rezende Ribeiro de Noronha, Sylvana Izaura Salyba Rendeiro de Reis, Thayane Oliveira Santos, Daisy Motta Chianca Júnior, Deoclécio Alves Silva Junior, Luiz Gonzaga da Menezes, Rodrigo Cunha Alvim de Rodrigues, Cibele Velloso |
Palavras-chave: | Obesity Stress Thermoregulatory responses Heart rate Anxiety-like behavior |
Data do documento: | 2023 |
Referência: | SANTOS, A. R. C. et al. Thermoregulatory responses, heart rate, and the susceptibility to anxiety in obese animals subjected to stress. Physiology & Behavior, v. 266, artigo 114181, jul. 2023. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0031938423001099>. Acesso em: 01 ago. 2023. |
Resumo: | Obesity and stress are related to cardiovascular diseases. Rats fed a high-fat diet (HFD) show increased cardiovascular reactivity to emotional stress and altered defensive behavioral responses. Indeed, changes in thermoregulatory responses in an aversive environment are observed in these animals. However, studies aimed at clarifying the physiological mechanisms linking obesity, stress hyperreactivity and behavioral changes are needed. The aim of this study was to evaluate the changes in thermoregulatory responses, heart rate, and the susceptibility to anxiety in obese animals subjected to stress. Nine-week high-fat diet protocol was effective in inducing obesity by increasing weight gain, fat mass, adiposity index, white epididymal, retroperitoneal, inguinal and brown adipose tissue. Animals induced to obesity and subjected to stress (HFDS group) by the intruder animal method showed increases in heart rate (HR), core body temperature and tail temperature. HFDS showed an increase in the first exposure to the closed arm (anxiety-like behavior) in elevated T-Maze (ETM). The groups did not differ with respect to panic behavior assessed in the ETM and locomotor activity in the open field test. Our study shows that HFDS animals presented increased reactivity to stress with higher stress hyperthermia and anxious behavior. Thus, our results present relevant information regarding stress responsiveness and behavioral changes in obese animals. |
URI: | http://www.repositorio.ufop.br/jspui/handle/123456789/17944 |
Link para o artigo: | https://www.sciencedirect.com/science/article/pii/S0031938423001099 |
DOI: | https://doi.org/10.1016/j.physbeh.2023.114181 |
ISSN: | 0031-9384 |
Aparece nas coleções: | DECBI - Artigos publicados em periódicos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
---|---|---|---|---|
ARTIGO_ThermoregulatoryResponsesHeart.pdf Restricted Access | 3,05 MB | Adobe PDF | Visualizar/Abrir |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.